A promising approach in laser vitrectomy executed by plasma-mediated removal of vitreous body via a diode-pumped Q-switched Nd:YAG laser.

Daniel Uthoff, Rita Oravecz, Romina Kuehnl, Friederike Rubin-Schwarz, Matthias Frentzen, Norbert Schrage, Jörg Meister

Open access · goldAbstract read

In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

1.1field-weighted citation impact, top 18% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 11 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Daniel UthoffAachen Center of Technology Transfer in Ophthalmology (ACTO E.V.), An-Institute RWTH Aachen University, Karlsburgweg 9, 52070, Aachen, Germany. uthoff@acto.de.

Rita OraveczAachen Center of Technology Transfer in Ophthalmology (ACTO E.V.), An-Institute RWTH Aachen University, Karlsburgweg 9, 52070, Aachen, Germany.

Romina KuehnlUniversity of Applied Sciences Ansbach, Ansbach, Germany.

Friederike Rubin-SchwarzInstitute of Biomedical Optics, University of Lübeck, Lübeck, Germany.

Matthias FrentzenDepartment of Operative and Preventive Dentistry, Bonn University, Bonn, Germany.

Norbert SchrageAachen Center of Technology Transfer in Ophthalmology (ACTO E.V.), An-Institute RWTH Aachen University, Karlsburgweg 9, 52070, Aachen, Germany.

Jörg MeisterCenter of Dento-Maxillo-Facial Medicine, Bonn University, Bonn, Germany.

RWTH Aachen University · DEUniversity of Bonn · DEAnsbach University of Applied Sciences · DEUniversity of Lübeck · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To examine the applicability of plasma-mediated vitreous body removal, a diode-pumped Q-switched Neodymium:YAG laser was used for a possible application in eye surgery/vitrectomy. On a total of 1500 porcine vitreous bodies, removal rates were evaluated by comparing different LaserVit-tip designs (Mark I/II Gauge 19 and Mark III Gauge 22). The Nd:YAG laser, operating at a wavelength of 1064 nm and a pulse duration of 4 ns, was utilized for vitreous body removal with respective settings of 2, 3 and 4 mJ and pulse repetition rates (cut rates) from 5 to 25 Hz (300-1500 /min) in 5 Hz-steps as well as for 100 Hz (6000 cuts/min). The exposure times were selected at 10, 20, 40 and 60 s, respectively. Comparative measurements were carried out with mechanical cutters (Gauge 20 and Gauge 23), applying a fixed cut rate of 800 /min (13.33 Hz) at identical exposure times. The LaserVit-tips showed successful vitreous body removal for all laser settings and exposure times (Mark I: 6.2 g/min, Mark II: 8.2 g/min at 1500 cuts/min and 3 mJ, Mark II: 10.1 g/min, Mark III: 3.6 g/min at 6000 cuts/min at 3 mJ). Similar tip-dimensions (Gauge 22

Identifiers

PMID33303956

DOI10.1038/s41598-020-78878-y

PMCPMC7730428

OpenAlexW3111916096

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.