Evidence map›Paper›PMID 33303895›Full record

ArticleScientific reports2020

Optimization of the spherical integrity for sustained-release alginate microcarriers-encapsulated doxorubicin by the Taguchi method.

C T Pan, S T Chien, T C Chiang, C K Yen, S Y Wang, Z H Wen, C Y Yu, Y L Shiue

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

C T PanDepartment of Mechanical and Electro-Mechanical Engineering, National Sun Yat-Sen University, Kaohsiung, Taiwan.
S T ChienInstitute of Medical Science and Technology, National Sun Yat-Sen University, Kaohsiung, Taiwan.
T C ChiangInstitute of Biomedical Sciences, National Sun Yat-Sen University, Kaohsiung, Taiwan.
C K YenDepartment of Mechanical and Electro-Mechanical Engineering, National Sun Yat-Sen University, Kaohsiung, Taiwan.
S Y WangDepartment of Mechanical and Electro-Mechanical Engineering, National Sun Yat-Sen University, Kaohsiung, Taiwan.
Z H WenDepartment of Marine Biotechnology and Resources, National Sun Yat-Sen University, Kaohsiung, Taiwan.
C Y YuLiver Transplantation Program and Departments of Diagnostic Radiology and Surgery, Kaohsiung Chang Gung Memorial Hospital, and Chang Gung University College of Medicine, Kaohsiung, Taiwan. y7192215@ms17.hinet.net.
Y L ShiueInstitute of Biomedical Sciences, National Sun Yat-Sen University, Kaohsiung, Taiwan. shirley@imst.nsysu.edu.tw.
National Sun Yat-sen University · TWKaohsiung Armed Forces General Hospital · TWKaohsiung Chang Gung Memorial Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to develop biodegradable calcium alginate microcarriers with uniform particle size and spherical integrity for sustained-release targeting transarterial chemoembolization. To determine related parameters including the ratio of cross-linking volume (sodium alginate: CaCl

Indexed as

AlginatesCapsulesDrug CarriersMicrospheresCarcinoma, HepatocellularCell Line, TumorCell SurvivalChemoembolization, TherapeuticDelayed-Action PreparationsDoxorubicinHumansLiver NeoplasmsParticle SizeAlginatesCapsulesDelayed-Action PreparationsDoxorubicinDrug Carriers

Identifiers

PMID33303895
PMCPMC7729399
OpenAlexW3112085710

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.