ArticleScientific reports2020
Multi-omic approach provides insights into osmoregulation and osmoconformation of the crab Scylla paramamosain.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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15 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Free amino acids in response to salinity changes in fishes: relationships to osmoregulation.Fish physiology and biochemistry · 2023Pooled it
- Integrated Physiological, Transcriptomic, and Gut Microbial Responses of Chinese Mitten Crab (Eriocheir sinensis) to Acute Salinity Stress.Marine biotechnology (New York, N.Y.) · 2026Article
- Comparative Proteomics of Salinity Stress Responses in Fish and Aquatic Invertebrates.Proteomics · 2025Review
- An Integrated Transcriptomic and Proteomic Approach Uncovers the Molecular Mechanisms of Hypoosmotic Adaptation inInternational journal of molecular sciences · 2025Article
- Effects of dietary long-chain polyunsaturated fatty acids on osmoregulation and salinity adaptation in red tilapia (Oreochromis mossambicus♀ × O. niloticus♂) under salinity stress.Fish physiology and biochemistry · 2025Article
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- Resilience of circuits to environmental challenge.Current opinion in neurobiology · 2024Review
- Ionic regulatory strategies of crabs: the transition from water to land.Frontiers in physiology · 2024Review
- Multidimensional plasticity jointly contributes to rapid acclimation to environmental challenges during biological invasions.RNA (New York, N.Y.) · 2023Article
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- A Multi-Species Comparison and Evolutionary Perspectives on Ion Regulation in the Antennal Gland of Brachyurans.Frontiers in physiology · 2022Review
- Activated polymorphonuclear derived extracellular vesicles are potential biomarkers of periprosthetic joint infection.PloS one · 2022Article
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- Genome-Wide Transcriptional Responses of Marine NematodeFrontiers in physiology · 2021Article
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Osmoregulation and osmoconformation are two mechanisms through which aquatic animals adapt to salinity fluctuations. The euryhaline crab Scylla paramamosain, being both an osmoconformer and osmoregulator, is an excellent model organism to investigate salinity adaptation mechanisms in brachyurans. In the present study, we used transcriptomic and proteomic approaches to investigate the response of S. paramamosain to salinity stress. Crabs were transferred from a salinity of 25 ppt to salinities of 5 ppt or 33 ppt for 6 h and 10 days. Data from both approaches revealed that exposure to 5 ppt resulted in upregulation of ion transport and energy metabolism associated genes. Notably, acclimation to low salinity was associated with early changes in gene expression for signal transduction and stress response. In contrast, exposure to 33 ppt resulted in upregulation of genes related to amino acid metabolism, and amino acid transport genes were upregulated only at the early stage of acclimation to this salinity. Our study reveals contrasting mechanisms underlying osmoregulation and osmoconformation within the salinity range of 5-33 ppt in the mud crab, and provides novel candidate genes for osmotic signal transduction, thereby providing insights on understanding the salinity adaptation mechanisms of brachyuran crabs.
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