ArticleNature communications2020
Diffuse neural coupling mediates complex network dynamics through the formation of quasi-critical brain states.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 54 citations in OpenAlex.
- Thalamic modulation of cortical linearity across arousal states.Science advances · 2026Article
- Modeling the influences of non-local connectomic projections on geometrically constrained cortical dynamics.PLoS computational biology · 2026Article
- The biological role of local and global fMRI BOLD signal variability in multiscale human brain organization.Nature communications · 2026Article
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- A burst-dependent thalamocortical substrate for perceptual awareness.PLoS computational biology · 2025Article
- Symmetry breaking organizes the brain's resting state manifold.Scientific reports · 2024Article
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- Dynamic Phase Transition in 2D Ising Systems: Effect of Anisotropy and Defects.Entropy (Basel, Switzerland) · 2024Article
- A thalamocortical substrate for integrated information via critical synchronous bursting.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Neuronal connected burst cascades bridge macroscale adaptive signatures across arousal states.Nature communications · 2023Article
- The biological role of local and global fMRI BOLD signal variability in human brain organization.bioRxiv : the preprint server for biology · 2023Article
- Canonical circuit computations for computer vision.Biological cybernetics · 2023Review
- Computational modelling in disorders of consciousness: Closing the gap towards personalised models for restoring consciousness.NeuroImage · 2023Article
- The impact of the human thalamus on brain-wide information processing.Nature reviews. Neuroscience · 2023Review
- Neuromodulatory control of complex adaptive dynamics in the brain.Interface focus · 2023Review
- A whole new world: embracing the systems-level to understand the indirect impact of pathology in neurodegenerative disorders.Journal of neurology · 2023Review
- Structural connections between the noradrenergic and cholinergic system shape the dynamics of functional brain networks.NeuroImage · 2022Article
- Edge-based network analysis reveals frequency-specific network dynamics in aberrant anxiogenic processing in rats.Network neuroscience (Cambridge, Mass.) · 2022Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The biological mechanisms that allow the brain to balance flexibility and integration remain poorly understood. A potential solution may lie in a unique aspect of neurobiology, which is that numerous brain systems contain diffuse synaptic connectivity. Here, we demonstrate that increasing diffuse cortical coupling within a validated biophysical corticothalamic model traverses the system through a quasi-critical regime in which spatial heterogeneities in input noise support transient critical dynamics in distributed subregions. The presence of quasi-critical states coincides with known signatures of complex, adaptive brain network dynamics. Finally, we demonstrate the presence of similar dynamic signatures in empirical whole-brain human neuroimaging data. Together, our results establish that modulating the balance between local and diffuse synaptic coupling in a thalamocortical model subtends the emergence of quasi-critical brain states that act to flexibly transition the brain between unique modes of information processing.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.