Evidence map›Paper›PMID 33303717›Full record

ArticleAnnals of laboratory medicine2021

Serum Ferritin as a Diagnostic Biomarker for Kawasaki Disease.

Sung Hoon Kim, Eun Song Song, Somy Yoon, Gwang Hyeon Eom, Gaeun Kang, Young Kuk Cho

Abstract read
In one paragraph

Article in Annals of laboratory medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  13. Infliximab treatment for refractory COVID-19-associated multisystem inflammatory syndrome in a Japanese child.Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sung Hoon KimDepartment of Pediatrics, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Korea.ORCID https://orcid.org/0000-0002-2128-2874
Eun Song SongDepartment of Pediatrics, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju, Korea.ORCID https://orcid.org/0000-0003-1056-2165
Somy YoonDepartment of Pharmacology and Medical Research Center for Gene Regulation, Chonnam National University Medical School, Hwasun-gun, Jeollanam-do, Korea.ORCID https://orcid.org/0000-0001-7393-5040
Gwang Hyeon EomDepartment of Pharmacology and Medical Research Center for Gene Regulation, Chonnam National University Medical School, Hwasun-gun, Jeollanam-do, Korea.ORCID https://orcid.org/0000-0002-7904-8503
Gaeun KangDivision of Clinical Pharmacology, Chonnam National University Hospital, Gwangju, Korea.ORCID https://orcid.org/0000-0001-9841-1139
Young Kuk ChoDepartment of Pediatrics, College of Medicine Chosun University, Gwangju, Korea.ORCID https://orcid.org/0000-0001-6811-2883

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diagnosis of Kawasaki disease (KD) is occasionally delayed because it is solely based on clinical symptoms. Previous studies have attempted to identify diagnostic biomarkers for KD. Recently, patients with KD were reported to have elevated serum ferritin levels. We investigated the usefulness of the serum ferritin level as a diagnostic biomarker for distinguishing KD from other acute febrile illnesses. Blood samples were obtained from pediatric patients with KD (N=77) and those with other acute febrile illnesses (N=32) between December 2007 and June 2011 for measuring various laboratory parameters, including serum ferritin levels. In patients with KD, laboratory tests were performed at diagnosis and repeated at 2, 14, and 56 days after intravenous immunoglobulin treatment. At the time of diagnosis, serum ferritin levels in patients with KD (188.8 μg/L) were significantly higher than those in patients with other acute febrile illnesses (106.8 μg/L,

Indexed as

Mucocutaneous Lymph Node SyndromeBiomarkersChildFemaleFerritinsHumansMaleSensitivity and SpecificityBiomarkersFerritinsBiomarkerDiagnosisFerritinKawasaki disease

Identifiers

PMID33303717
PMCPMC7748097

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.