Evidence map›Paper›PMID 33303701›Full record

ArticleCurrent issues in molecular biology2021

Lyme Disease in Humans.

Justin D Radolf, Klemen Strle, Jacob E Lemieux, Franc Strle

Open access · goldAbstract read
In one paragraph

Article in Current issues in molecular biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 100 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
100citing papers in PubMed, 1 pooled it
9.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

100 citing papers in PubMed, 1 synthesis or guideline pooled it, 110 citations in OpenAlex.

  1. Incidence of Lyme Borreliosis in Europe: A Systematic Review (2005-2020).Vector borne and zoonotic diseases (Larchmont, N.Y.) · 2023
    Pooled it
  2. Trial
  3. Review
  4. Review
  5. Colonization of 3D-organotypic human skin by the Lyme Disease pathogen,bioRxiv : the preprint server for biology · 2026
    Article
  6. Review
  7. Review
  8. Anti-Pathogens (Basel, Switzerland) · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. TheInfection and immunity · 2026
    Article
  13. Article
  14. Prevalence and Risk Factors ofPathogens (Basel, Switzerland) · 2026
    Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Prevalence ofPathogens (Basel, Switzerland) · 2025
    Article

40 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Justin D RadolfMedicine, UConn Health, Farmington, CT 06030, USA.
Klemen StrleDivision of Infectious Diseases, Wadsworth Center, NY Department of Health, Albany NY, 12208, USA.
Jacob E LemieuxDepartment of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Franc StrleDepartment of Infectious Diseases, University Medical Center Ljubljana, Ljubljana, Slovenia.
Harvard University · USLjubljana University Medical Centre · SIUConn Health · USWadsworth Center · US

Funding

RpoS Regulation of Borrelia burgdorferi Genes in vivoR01AI029735 · NIAID · UNIVERSITY OF TEXAS SW MED CTR/DALLAS · PI CAIMANO, MELISSA J, RADOLF, JUSTIN D · 1990 to 2022
$10.7M
Microbial Determinants of Clinical Heterogeneity in Lyme DiseaseR00AI148604 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI LEMIEUX, JACOB ERIC · 2022 to 2023
$500k
Borrelia burgdorferi oligopeptide (Opp) transporter control of cellular homeostasis and growthR21AI139940 · NIAID · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI CAIMANO, MELISSA J, RADOLF, JUSTIN D · 2018 to 2019
$439k
Microbial genetic variation in the pathogenesis of Lyme DiseaseR21AI149278 · NIAID · WADSWORTH CENTER · PI LIN, YI-PIN, STRLE, KLEMEN · 2020 to 2021
$426k
Microbial Determinants of Clinical Heterogeneity in Lyme DiseaseK99AI148604 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI LEMIEUX, JACOB ERIC · 2020 to 2021
$273k
NIAID NIH HHS K99 AI148604NIAID NIH HHS R00 AI148604NIAID NIH HHS R01 AI029735NIAID NIH HHS R21 AI139940NIAID NIH HHS R21 AI149278
6 · The paper itself

Abstract

Lyme disease (Lyme borreliosis) is a tick-borne, zoonosis of adults and children caused by genospecies of the

Indexed as

Borrelia burgdorferiAnimalsArthropod VectorsDisease ManagementDisease SusceptibilityHost-Pathogen InteractionsHumansLife Cycle StagesLyme DiseaseOrgan SpecificityTicks

Identifiers

PMID33303701
PMCPMC7946767
OpenAlexW3091864377

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.