Evidence map›Paper›PMID 33303677›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2021

High Salt Intake Recruits Tonic Activation of NR2D Subunit-Containing Extrasynaptic NMDARs in Vasopressin Neurons.

Chiranjivi Neupane, Ramesh Sharma, Yoon Hyung Pai, So Yeong Lee, Byeong Hwa Jeon, Hyun-Woo Kim, Javier E Stern, Jin Bong Park

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Role of the STING→IRF3 Pathway in Ambient GABA Homeostasis and Cognitive Function.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  4. Article
  5. Article
  6. Tonic Activation of NR2D-Containing NMDARs Exacerbates Dopaminergic Neuronal Loss in MPTP-Injected Parkinsonian Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  7. Article
  8. Article
  9. NMDA Receptors in the Lateral Preoptic Hypothalamus Are Essential for Sustaining NREM and REM Sleep.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Chiranjivi NeupaneDepartment of Physiology, Chungnam National University, Daejeon 35015, Republic of Korea.ORCID 0000-0003-2719-9331
Ramesh SharmaDepartment of Physiology, Chungnam National University, Daejeon 35015, Republic of Korea.
Yoon Hyung PaiDepartment of Physiology, Chungnam National University, Daejeon 35015, Republic of Korea.
So Yeong LeeLaboratory of Veterinary Pharmacology, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul 151-742, Republic of Korea.
Byeong Hwa JeonDepartment of Physiology, Chungnam National University, Daejeon 35015, Republic of Korea.
Hyun-Woo KimDepartment of Physiology, Chungnam National University, Daejeon 35015, Republic of Korea.
Javier E SternNeuroscience Institute, Georgia State University, Atlanta, Georgia 30302.
Jin Bong ParkDepartment of Physiology, Chungnam National University, Daejeon 35015, Republic of Korea jinbong@cnu.ac.kr.
Chungnam National University · KRGeorgia State University · USSeoul National University · KR

Funding

DENDRITIC RELEASE OF NEUROPEPTIDES: ROLE IN BODILY HOMEOSTASISR01NS094640 · NINDS · GEORGIA STATE UNIVERSITY · PI STERN, JAVIER E · 2016 to 2020
$1.4M
NINDS NIH HHS R01 NS094640
6 · The paper itself

Abstract

In addition to producing a classical excitatory postsynaptic current via activation of synaptic NMDA receptors (NMDARs), glutamate in the brain also induces a tonic NMDAR current (

Indexed as

AnimalsExcitatory Amino Acid AntagonistsExcitatory Postsynaptic PotentialsMaleMiceMice, Inbred C57BLMice, KnockoutNeuronsRatsRats, Sprague-DawleyRats, TransgenicRats, WistarReceptors, N-Methyl-D-AspartateSodium Chloride, DietarySynapsesVasopressinsExcitatory Amino Acid AntagonistsNR2D NMDA receptorReceptors, N-Methyl-D-AspartateSodium Chloride, DietaryVasopressinsiMK801NR2Doxytocinsalt loadingtonic NMDAvasopressin

Identifiers

PMID33303677
PMCPMC7888215
OpenAlexW3111835971

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.