Evidence map›Paper›PMID 33303521›Full record

ArticleAJNR. American journal of neuroradiology2021

Pediatric Head CT: Automated Quantitative Analysis with Quantile Regression.

K A Cauley, Y Hu, S W Fielden

Open access · hybridAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Age and sex estimation using post-mortem CT scout view.International journal of legal medicine · 2026
    Article
  2. Article
  3. Head CT: Toward Making Full Use of the Information the X-Rays Give.AJNR. American journal of neuroradiology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

K A CauleyFrom the Departments of Radiology (K.A.C.) keithcauley@hotmail.com.ORCID 0000-0002-0247-0650
Y HuBiomedical and Translational Informatics (Y.H.), Geisinger Medical Center, Danville, Pennsylvania.ORCID 0000-0002-0477-0155
S W FieldenGeisinger Autism and Developmental Medicine Institute (S.W.F.), Lewisburg, Pennsylvania.ORCID 0000-0002-5987-981X
Autism & Developmental Medicine Institute · USGeisinger Medical Center · USKema International (Netherlands) · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeTogether with quantile regression methods, such a model would have the potential for clinical utility through automated quantitative comparison of individual cases relative to their age and gender-matched peer group. Our aim was to demonstrate the automated processing of digital clinical head CT data in the development of a clinically useful model of age-related changes of the brain in the first 2 decades of life. MATERIALS AND

methodsA total of 415 (209 female) consecutive, clinical head CTs with radiographically normal findings from patients from birth through 20 years of age were retrospectively selected and subjected to automated segmentation. Brain volume, brain parenchymal fraction, brain radiodensity, and brain radiomass were assessed as a function of patient age. Statistical modeling and quantile regression were performed.

resultsBrain volume increased from 400 cm

conclusionsAutomated segmentation of clinical head CT images permitted the generation of a reference database for quantitative analysis of pediatric and adolescent brains. Quantile regression facilitates clinical application.

Indexed as

AdolescentBrainChildChild, PreschoolFemaleHeadHumansImage Interpretation, Computer-AssistedInfantInfant, NewbornMaleModels, StatisticalReference ValuesRetrospective StudiesTomography, X-Ray ComputedYoung Adult

Identifiers

PMID33303521
PMCPMC7872171
OpenAlexW3110961131

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.