Evidence map›Paper›PMID 33303519›Full record

ArticleAJNR. American journal of neuroradiology2021

Basal Ganglia versus Peripheral Infarcts: Predictive Value of Early Fiber Alterations.

M T Berndt, D Pürner, C Maegerlein, S Wunderlich, B Friedrich, C Zimmer, D Sepp, J Kaesmacher, T Boeckh-Behrens

Abstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

M T BerndtFrom the Departments of Neuroradiology (M.T.B., C.M., B.F., C.Z., D.S., T.B.-B.) maria.berndt@tum.de.ORCID 0000-0001-9124-231X
D PürnerNeurology (D.P., S.W.), Klinikum rechts der Isar, School of Medicine, Technical University of Munich, Munich, Germany.ORCID 0000-0003-4880-6575
C MaegerleinFrom the Departments of Neuroradiology (M.T.B., C.M., B.F., C.Z., D.S., T.B.-B.).ORCID 0000-0003-4885-7671
S WunderlichNeurology (D.P., S.W.), Klinikum rechts der Isar, School of Medicine, Technical University of Munich, Munich, Germany.ORCID 0000-0003-1208-3686
B FriedrichFrom the Departments of Neuroradiology (M.T.B., C.M., B.F., C.Z., D.S., T.B.-B.).ORCID 0000-0002-2198-9925
C ZimmerFrom the Departments of Neuroradiology (M.T.B., C.M., B.F., C.Z., D.S., T.B.-B.).ORCID 0000-0002-4805-9103
D SeppFrom the Departments of Neuroradiology (M.T.B., C.M., B.F., C.Z., D.S., T.B.-B.).ORCID 0000-0002-4565-4409
J KaesmacherDepartment of Neuroradiology (J.K.), Inselspital, University Hospital Bern, University Bern, Bern, Switzerland.ORCID 0000-0002-9177-2289
T Boeckh-BehrensFrom the Departments of Neuroradiology (M.T.B., C.M., B.F., C.Z., D.S., T.B.-B.).ORCID 0000-0003-0266-8947

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeImpairment of fiber integrity of the corticospinal tract in the subacute and chronic phases after ischemic stroke has been linked to poor motor outcome. The aim of the study was an assessment of fiber integrity in the acute poststroke phase and an evaluation of its association with the clinical course dependent on the infarction pattern (subtypes: peripheral versus basal ganglia infarction). MATERIALS AND

methodsAll patients who underwent mechanical recanalization of a large-vessel occlusion in the anterior circulation and postinterventional DTI were included (

resultsThe fractional anisotropy index was reduced in the acute poststroke phase with a correlation to clinical presentation, especially in case of peripheral infarcts (eg, with the NIHSS motor subscore:

conclusionsCorticospinal tract abnormalities can be observed in the early stage after mechanical recanalization and have prognostic capacity. This finding increases the clinical value of early DTI imaging parameters. Because the effects observed were limited to peripheral infarcts, further and longitudinal evaluation of fiber integrities within basal ganglia infarction is required.

Indexed as

AdultAgedBasal GangliaCerebral InfarctionDiffusion Tensor ImagingFemaleHumansMaleMiddle AgedPrognosisPyramidal Tracts

Identifiers

PMID33303519
PMCPMC7872162

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.