ArticleVirology journal2020
Comparative analysis of clinical features of SARS-CoV-2 and adenovirus infection among children.
Article in Virology journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 14 citations in OpenAlex.
- Seasonal Variation in Conjunctivitis in Saudi Arabia and Reduction of Searches During the COVID-19 Pandemic: Analysis of Google Trends Data.JMIR formative research · 2025Article
- COVID-19 pandemic: Impact on the rate of viral conjunctivitis.Archivos de la Sociedad Espanola de Oftalmologia · 2022Article
- [COVID-19 pandemic: Impact on the rate of viral conjunctivitis].Archivos de la Sociedad Espanola de Oftalmologia · 2022Article
- Global Research Trends in Pediatric COVID-19: A Bibliometric Analysis.Frontiers in public health · 2022Article
- Detection of human adenovirus among Iranian pediatric hospitalized patients suspected of COVID-19: epidemiology and comparison of clinical features.Le infezioni in medicina · 2022Article
- Computed tomography findings in 3,557 COVID-19 infected children: a systematic review.Quantitative imaging in medicine and surgery · 2021Review
- Potential Diagnostic and Prognostic Biomarkers for Adenovirus Respiratory Infection in Children and Young Adults.Viruses · 2021Review
- Comparison of clinical features on admission between coronavirus disease 2019 and influenza a among children: a retrospective study in China.BMC infectious diseases · 2021Article
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe new emerging coronavirus disease 2019 (COVID-19) overall shares similar symptoms with other common respiratory viral infections. We aimed in this study to compare COVID-19 and human adenovirus (HAdV) infections in pediatric patients regarding the frequencies of major clinical symptoms and the potential disparities in laboratory and imaging parameters.
methodsFollowing a case-control-like design, we built 72 age-matched pediatric COVID-19 and HAdV patient pairs. Their early symptoms and laboratory and imaging characteristics were then retrieved and compared.
resultsFever and cough were the most common symptoms for both infections but were seen more often in HAdV than in COVID-19 patients (92% vs. 66% and 60% vs. 18%, respectively). Compared with COVID-19 patients, children with HAdV infection had statistically significantly higher values of neutrophil count, neutrophil percentage, activated partial thromboplastin time, prothrombin time, lactate dehydrogenase, C-reactive protein, procalcitonin but lower values of lymphocyte percentage, total bilirubin, potassium and sodium. Thoracic computed tomography also revealed more anomalies in HAdV patients than in COVID-19 patients (95% vs. 67%).
conclusionsCOVID-19 is an overall less symptomatic and less severe infection at admission compared to HAdV respiratory infection in pediatric population.
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