Evidence map›Paper›PMID 33302575›Full record

ArticleJournal of clinical medicine2020

Magnetic-Activated Cell Sorting (MACS): A Useful Sperm-Selection Technique in Cases of High Levels of Sperm DNA Fragmentation.

Alberto Pacheco, Arancha Blanco, Fernando Bronet, María Cruz, Jaime García-Fernández, Juan Antonio García-Velasco

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 65 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Sperm Selection Procedures in Cases of High Sperm DNA Fragmentation Index.Advances in experimental medicine and biology · 2026
    Review
  12. Genetic and Epigenetic Risks of Male Infertility in ART.International journal of molecular sciences · 2025
    Review
  13. Sperm selection for assisted reproductive technology: do we have a winner?Journal of assisted reproduction and genetics · 2025
    Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Alberto PachecoIVI Madrid, 28023 Madrid, Spain.
Arancha BlancoIVI Salamanca, 37001 Salamanca, Spain.
Fernando BronetIVI Madrid, 28023 Madrid, Spain.
María CruzIVI Madrid, 28023 Madrid, Spain.
Jaime García-FernándezThe University of Edinburgh Medical School, Edinburgh EH8 9AG, UK.
Juan Antonio García-VelascoIVI Madrid, 28023 Madrid, Spain.ORCID 0000-0003-1005-8727
IVI Madrid Clinic · ESUniversidad Rey Juan Carlos · ESUniversity of Edinburgh · GBValencian Infertility Institute · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Magnetic-activated cell sorting (MACS) can be used to separate apoptotic sperm with high proportions of fragmented DNA from the rest, thus improving the overall quality of the seminal sample. Therefore, the aim of this retrospective study was to investigate the efficiency of the MACS technique to increase reproductive outcomes in patients with high levels of sperm DNA fragmentation (SDF) undergoing intracytoplasmic sperm-injection (ICSI) cycles. In this study, we analyzed a total of 724 assisted-reproduction-technique (ART) cycles that were divided into two groups: the study group (

Indexed as

ART outcomeMACSmagnetic-activated cell sortingmale infertilitymiscarriageSDFsperm DNA fragmentationsperm selection

Identifiers

PMID33302575
PMCPMC7763893
OpenAlexW3111673788

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.