Evidence map›Paper›PMID 33302572›Full record

ArticleAntioxidants (Basel, Switzerland)2020

Capsaicin, a Powerful

Adriana Pérez-González, Mario Prejanò, Nino Russo, Tiziana Marino, Annia Galano

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Adriana Pérez-GonzálezCONACYT-Universidad Autónoma Metropolitana-Iztapalapa, San Rafael Atlixco 186, Col. Vicentina, Iztapalapa, México City 09340, Mexico.
Mario PrejanòDepartment of Chemistry and Chemical Technologies, Università della Calabria (UNICAL), Calabria, 87036 Arcavacata di Rende, Italy.
Nino RussoDepartment of Chemistry and Chemical Technologies, Università della Calabria (UNICAL), Calabria, 87036 Arcavacata di Rende, Italy.ORCID 0000-0003-3826-3386
Tiziana MarinoDepartment of Chemistry and Chemical Technologies, Università della Calabria (UNICAL), Calabria, 87036 Arcavacata di Rende, Italy.ORCID 0000-0003-2386-9078
Annia GalanoDepartamento de Química, Universidad Autónoma Metropolitana-Iztapalapa, San Rafael Atlixco 186, Col. Vicentina, Iztapalapa, México City 09340, Mexico.

Funding

Italian Ministry of Foreign Affairs and International Cooperation Prot. nr. MAE00643232020-06-16 (PGR01085)
6 · The paper itself

Abstract

Oxidative conditions are frequently enhanced by the presence of redox metal ions. In this study, the role of capsaicin (8-methyl-N-vanillyl-6-nonenamide, CAP) in copper-induced oxidative stress was investigated using density functional theory simulations. It was found that CAP has the capability to chelate Cu(II), leading to complexes that are harder to reduce than free Cu(II). CAP fully turns off the Cu(II) reduction by Asc

Indexed as

capsaicinCu-complexesDFTfenton reactionmolecular dynamicsnatural antioxidantoxidative stress

Identifiers

PMID33302572
PMCPMC7763808

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.