Evidence map›Paper›PMID 33302535›Full record

ReviewJournal of fungi (Basel, Switzerland)2020

Biosensors and Diagnostics for Fungal Detection.

Khalil K Hussain, Dhara Malavia, Elizabeth M Johnson, Jennifer Littlechild, C Peter Winlove, Frank Vollmer, Neil A R Gow

Abstract readReview
In one paragraph

Review in Journal of fungi (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Review
  2. Review
  3. Cassette-Based Automated Production of 2-Deoxy-2-[Molecules (Basel, Switzerland) · 2026
    Article
  4. Fungal Infections in Pediatric Patients With Hematologic Malignancies and Stem Cell Transplantation: Impact on the Upper and Lower Respiratory Systems.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2026
    Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Microbiology and molecular biology reviews : MMBR · 2024
    Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. Cerebrospinal fluid: a target of some fungi and an overview.Memorias do Instituto Oswaldo Cruz · 2023
    Article
  18. Microfluidics combined with fluorescenceFrontiers in bioengineering and biotechnology · 2022
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Khalil K HussainMedical Research Council Centre for Medical Mycology, The University of Exeter University of Exeter, Geoffrey Pope Building, Stocker Road, Exeter EX4 4QD, UK.
Dhara MalaviaMedical Research Council Centre for Medical Mycology, The University of Exeter University of Exeter, Geoffrey Pope Building, Stocker Road, Exeter EX4 4QD, UK.
Elizabeth M JohnsonMedical Research Council Centre for Medical Mycology, The University of Exeter University of Exeter, Geoffrey Pope Building, Stocker Road, Exeter EX4 4QD, UK.
Jennifer LittlechildBiocatalysis Centre, University of Exeter, The Henry Wellcome Building for Biocatalysis, Stocker Road, University of Exeter, Exeter EX4 4QD, UK.
C Peter WinloveDepartment of Physics and Astronomy, College of Engineering, Mathematics and Physical Sciences, University of Exeter, Exeter EX4 4QD, UK.
Frank VollmerLiving Systems Institute, University of Exeter, Stocker Road, University of Exeter, Exeter EX4 4QD, UK.
Neil A R GowMedical Research Council Centre for Medical Mycology, The University of Exeter University of Exeter, Geoffrey Pope Building, Stocker Road, Exeter EX4 4QD, UK.

Funding

Engineering and Physical Sciences Research Council EP/T002875/1Medical Research Council MR/N006364/2Wellcome (101873/Z/13/Z), and (200208/A/15/Z)Wellcome Trust 200208/Z/15/Z
6 · The paper itself

Abstract

Early detection is critical to the successful treatment of life-threatening infections caused by fungal pathogens, as late diagnosis of systemic infection almost always equates with a poor prognosis. The field of fungal diagnostics has some tests that are relatively simple, rapid to perform and are potentially suitable at the point of care. However, there are also more complex high-technology methodologies that offer new opportunities regarding the scale and precision of fungal diagnosis, but may be more limited in their portability and affordability. Future developments in this field are increasingly incorporating new technologies provided by the use of new format biosensors. This overview provides a critical review of current fungal diagnostics and the development of new biophysical technologies that are being applied for selective new sensitive fungal biosensors to augment traditional diagnostic methodologies.

Indexed as

biosensorsdiagnosticsfungal biomarkerimmobilizationmedical mycologypoint-of-care devices

Identifiers

PMID33302535
PMCPMC7770582

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.