Evidence map›Paper›PMID 33302435›Full record

ArticleInternational journal of molecular sciences2020

Monosomy-3 Alters the Expression Profile of the Glucose Transporters GLUT1-3 in Uveal Melanoma.

Tjorge Maaßen, Siranush Vardanyan, Anton Brosig, Hartmut Merz, Mahdy Ranjbar, Vinodh Kakkassery, Salvatore Grisanti, Aysegül Tura

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Tjorge MaaßenDepartment of Ophthalmology, University of Lübeck, Ratzeburger Allee 160, 23538 Lübeck, Germany.
Siranush VardanyanDepartment of Ophthalmology, University of Lübeck, Ratzeburger Allee 160, 23538 Lübeck, Germany.ORCID 0000-0001-7767-5004
Anton BrosigDepartment of Ophthalmology, University of Lübeck, Ratzeburger Allee 160, 23538 Lübeck, Germany.
Hartmut MerzReference Center for Lymph Node Pathology and Haematopathology, 23562 Lübeck, Germany.
Mahdy RanjbarDepartment of Ophthalmology, University of Lübeck, Ratzeburger Allee 160, 23538 Lübeck, Germany.
Vinodh KakkasseryDepartment of Ophthalmology, University of Lübeck, Ratzeburger Allee 160, 23538 Lübeck, Germany.ORCID 0000-0001-6212-8964
Salvatore GrisantiDepartment of Ophthalmology, University of Lübeck, Ratzeburger Allee 160, 23538 Lübeck, Germany.
Aysegül TuraDepartment of Ophthalmology, University of Lübeck, Ratzeburger Allee 160, 23538 Lübeck, Germany.
University of Lübeck · DE

Funding

University Clinic Lübeck FC20222Werner and Klara-Kreitz Stiftung, Germany F279097
6 · The paper itself

Abstract

Monosomy-3 in uveal melanoma (UM) cells increases the risk of fatal metastases. The gene encoding the low-affinity glucose transporter GLUT2 resides on chromosome 3q26.2. Here, we analyzed the expression of the glucose transporters GLUT1, GLUT2, and GLUT3 with regard to the histological and clinical factors by performing immunohistochemistry on the primary tumors of

Indexed as

Chromosome DeletionAgedAged, 80 and overBiomarkers, TumorCells, CulturedChromosomes, Human, Pair 3FemaleGlucose Transport Proteins, FacilitativeHumansMaleMelanomaMiddle AgedNeoplasm MetastasisNeoplastic Cells, CirculatingUveal MelanomaUveal NeoplasmsBiomarkers, TumorGlucose Transport Proteins, Facilitativeglucose transportGLUT1GLUT2GLUT3monosomy-3uveal melanoma

Identifiers

PMID33302435
PMCPMC7762573
OpenAlexW3111098811

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.