Evidence map›Paper›PMID 33302367›Full record

ReviewInternational journal of molecular sciences2020

The Impact of Angiogenesis in the Most Common Salivary Gland Malignant Tumors.

Despoina Pouloudi, Aristoteles Sotiriadis, Margarita Theodorakidou, Panagiotis Sarantis, Alexandros Pergaris, Michalis V Karamouzis, Stamatios Theocharis

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Despoina PouloudiFirst Department of Pathology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Aristoteles SotiriadisFirst Department of Pathology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Margarita TheodorakidouFirst Department of Pathology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Panagiotis SarantisMolecular Oncology Unit, Department of Biological Chemistry, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Alexandros PergarisFirst Department of Pathology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Michalis V KaramouzisMolecular Oncology Unit, Department of Biological Chemistry, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0000-0003-1369-8201
Stamatios TheocharisFirst Department of Pathology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
National and Kapodistrian University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Salivary gland carcinomas (SGCs) represent a group of rare tumors, with complete surgical resection being the main treatment option. Therapeutic armory for cases of locally aggressive, recurrent, and/or metastatic SGCs, though, remains poor since they exhibit high rates of resistance to systematic therapy. Angiogenesis is considered one of the contemporary hallmarks of cancer and anti-angiogenic factors have already been approved for the treatment of several cancer types. This review aims to summarize, in a histotype-specific manner, the most current available data on the angiogenic factors implicated in SGC angiogenesis, in order to highlight the differences between the most common SGC histotypes and the factors that may have a potential role as therapeutic targets.

Indexed as

Angiogenesis InhibitorsAntineoplastic AgentsCarcinomaHumansNeovascularization, PathologicSalivary Gland NeoplasmsAngiogenesis InhibitorsAntineoplastic Agentsangiogenesisangiogenic factorsanti-angiogenic factorshistotypessalivary gland tumortherapy

Identifiers

PMID33302367
PMCPMC7762607
OpenAlexW3111751733

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.