ArticleInternational journal of molecular sciences2020
AmOctα2R: Functional Characterization of a Honeybee Octopamine Receptor Inhibiting Adenylyl Cyclase Activity.
Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 20 citations in OpenAlex.
- Virus specific impacts on honey bee flight performance are mediated by the octopamine pathway.bioRxiv : the preprint server for biology · 2026Article
- Inapparent virus infections differentially affect honey bee flight.Science advances · 2025Article
- Tyramine and itseLife · 2023Article
- Visual learning in tethered bees modifies flight orientation and is impaired by epinastine.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2023Article
- Molecular and Pharmacological Characterization of β-Adrenergic-like Octopamine Receptors in the EndoparasitoidInternational journal of molecular sciences · 2022Article
- Article
- Examination of Intracellular GPCR-Mediated Signaling with High Temporal Resolution.International journal of molecular sciences · 2022Article
- Biological functions of α2-adrenergic-like octopamine receptor in Drosophila melanogaster.Genes, brain, and behavior · 2022Article
- Octopamine drives honeybee thermogenesis.eLife · 2022Article
- PaOctβ2R: Identification and Functional Characterization of an Octopamine Receptor Activating Adenylyl Cyclase Activity in the American CockroachInternational journal of molecular sciences · 2022Article
- Opposing Actions of Octopamine and Tyramine on Honeybee Vision.Biomolecules · 2021Article
- G-Protein Coupled Receptors (GPCRs): Signaling Pathways, Characterization, and Functions in Insect Physiology and Toxicology.International journal of molecular sciences · 2021Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The catecholamines norepinephrine and epinephrine are important regulators of vertebrate physiology. Insects such as honeybees do not synthesize these neuroactive substances. Instead, they use the phenolamines tyramine and octopamine for similar physiological functions. These biogenic amines activate specific members of the large protein family of G protein-coupled receptors (GPCRs). Based on molecular and pharmacological data, insect octopamine receptors were classified as either α- or β-adrenergic-like octopamine receptors. Currently, one α- and four β-receptors have been molecularly and pharmacologically characterized in the honeybee. Recently, an α
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.