Evidence map›Paper›PMID 33302094›Full record

ArticleSleep medicine2021

Impact of home confinement during COVID-19 pandemic on sleep parameters in Parkinson's disease.

Niraj Kumar, Ravi Gupta, Hrishikesh Kumar, Sahil Mehta, Roopa Rajan, Deva Kumar, Rukmini Mridula Kandadai, Soaham Desai, Pettarusp Wadia, Purba Basu and 8 more

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In one paragraph

Article in Sleep medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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  4. Psychological outcomes of the COVID-19 pandemic in patients with Parkinson's disease: A systematic review.Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia · 2022
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  17. Spotlight on non-motor symptoms and Covid-19.International review of neurobiology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Niraj KumarDept. of Neurology and Division of Sleep Medicine, All India Institute of Medical Sciences, Rishikesh, India. Electronic address: drnirajkumarsingh@gmail.com.
Ravi GuptaDept. of Psychiatry and Division of Sleep Medicine, All India Institute of Medical Sciences, Rishikesh, India.
Hrishikesh KumarDept. of Neurology, Institute of Neurosciences, Kolkata, India.
Sahil MehtaDept. of Neurology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Roopa RajanDept. of Neurology, All India Institute of Medical Sciences, New Delhi, India.
Deva KumarCenter for Parkinson's Disease and Movement Disorders, Vikram Hospital, Bengaluru, India.
Rukmini Mridula KandadaiDept. of Neurology, Nizams Institute of Medical Sciences, Hyderabad, India.
Soaham DesaiDept. of Neurology, Shree Krishna Hospital, Karamsad, Anand, India.
Pettarusp WadiaDept. of Neurology, Jaslok Hospital, Mumbai, India.
Purba BasuDept. of Neurology, Institute of Neurosciences, Kolkata, India.
Banashree MondalDept. of Neurology, Institute of Neurosciences, Kolkata, India.
Sanchita JunejaDept. of Neurology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Ankita RawatDept. of Neurology and Division of Sleep Medicine, All India Institute of Medical Sciences, Rishikesh, India.
Sai Srilakshmi MekaDept. of Neurology, Nizams Institute of Medical Sciences, Hyderabad, India.
Bhushan MishalDept. of Neurology, Jaslok Hospital, Mumbai, India.
L K PrashanthCenter for Parkinson's Disease and Movement Disorders, Vikram Hospital, Bengaluru, India.
Achal Kumar SrivastavaDept. of Neurology, All India Institute of Medical Sciences, New Delhi, India.
Vinay GoyalDept. of Neurology, Medanta Hospital, Gurugram, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLiterature shows that home confinement during coronavirus disease 2019 (COVID-19) pandemic has significantly affected sleep. However, such information regarding subjects having Parkinson's disease (PD) is unavailable.

methodsThis cross-sectional study was conducted using a questionnaire, developed and validated by experts. PD subjects from nine centers across India were included. Questionnaire assessed presence as well as change in sleep-related parameters and PD symptoms during home confinement. Restless legs syndrome (RLS) and REM sleep behavior disorder (REMBD) was diagnosed using validated questionnaire. Additionally, changes in physical activity, adoption of new hobbies during home confinement and perceived quality of life were assessed.

resultsOf 832 subjects, 35.4% reported sleep disturbances. New-onset/worsening of sleep disturbances (NOWS) was reported by 23.9% subjects. Among those with sleep disturbances (n = 295), insomnia symptoms worsened in half (51.5%) and nearly one-fourth reported worsening of RLS (24.7%) and REMBD (22.7%) each. NOWS was common in subjects lacking adequate family support during home confinement (P = 0.03); home confinement > 60 days (P = 0.05) and duration of PD > 7 years (P = 0.008). Contrarily, physical activity >1 h/day and engagement in new hobbies during home confinement were associated with better sleep. NOWS was associated with worsening of motor as well as non-motor symptoms of PD (P < 0.001) and poorer life quality (P < 0.001).

conclusionHome confinement during COVID-19 pandemic was significantly associated with NOWS among PD subjects. NOWS was associated with global worsening of PD symptoms and poorer life quality. Physical activity >1 h/day and adoption of new hobbies during home confinement were associated with better sleep.

Indexed as

ComorbidityCOVID-19Cross-Sectional StudiesDisease ProgressionFemaleHumansIndiaMaleParkinson DiseaseQuality of LifeRestless Legs SyndromeSleep Wake DisordersSurveys and QuestionnairesCOVID-19DopamineHome confinementPandemicParkinson's disease

Identifiers

PMID33302094
PMCPMC7682933

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.