Evidence map›Paper›PMID 33302029›Full record

ArticleEuropean journal of radiology2021

Fully automatic framework for comprehensive coronary artery calcium scores analysis on non-contrast cardiac-gated CT scan: Total and vessel-specific quantifications.

Nan Zhang, Guang Yang, Weiwei Zhang, Wenjing Wang, Zhen Zhou, Heye Zhang, Lei Xu, Yundai Chen

Abstract read
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Article in European journal of radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

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  19. Automated coronary artery calcium scoring using nested U-Net and focal loss.Computational and structural biotechnology journal · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nan ZhangDepartment of Radiology, Beijing Anzhen Hospital, Capital Medical University, 2(nd) Anzhen Road, Chaoyang District, Beijing, China.
Guang YangCardiovascular Research Centre, Royal Brompton Hospital, SW3 6NP, London, UK; National Heart and Lung Institute, Imperial College London, London, SW7 2AZ, UK.
Weiwei ZhangSchool of Biomedical Engineering, Sun Yat-Sen University, China.
Wenjing WangDepartment of Radiology, Beijing Anzhen Hospital, Capital Medical University, 2(nd) Anzhen Road, Chaoyang District, Beijing, China.
Zhen ZhouDepartment of Radiology, Beijing Anzhen Hospital, Capital Medical University, 2(nd) Anzhen Road, Chaoyang District, Beijing, China.
Heye ZhangSchool of Biomedical Engineering, Sun Yat-Sen University, China.
Lei XuDepartment of Radiology, Beijing Anzhen Hospital, Capital Medical University, 2(nd) Anzhen Road, Chaoyang District, Beijing, China. Electronic address: leixu2001@hotmail.com.
Yundai ChenDepartment of Cardiology, Chinese PLA General Hospital, Beijing, China.

Funding

British Heart Foundation PG/16/78/32402
6 · The paper itself

Abstract

objectivesTo develop a fully automatic multiview shape constraint framework for comprehensive coronary artery calcium scores (CACS) quantification via deep learning on nonenhanced cardiac CT images.

methodsIn this retrospective single-centre study, a multi-task deep learning framework was proposed to detect and quantify coronary artery calcification from CT images collected between October 2018 and March 2019. A total of 232 non-contrast cardiac-gated CT scans were retrieved and studied (80 % for model training and 20 % for testing). CACS results of testing datasets (n = 46), including Agatston score, calcium volume score, calcium mass score, were calculated fully automatically and manually at total and vessel-specific levels, respectively.

resultsNo significant differences were found in CACS quantification obtained using automatic or manual methods at total and vessel-specific levels (Agatston score: automatic 535.3 vs. manual 542.0, P = 0.993; calcium volume score: automatic 454.2 vs. manual 460.6, P = 0.990; calcium mass score: automatic 128.9 vs. manual 129.5, P = 0.992). Compared to the ground truth, the number of calcified vessels can be accurate recognized automatically (total: automatic 107 vs. manual 102, P = 0.125; left main artery: automatic 15 vs. manual 14, P = 1.000 ; left ascending artery: automatic 37 vs. manual 37, P = 1.000; left circumflex artery: automatic 22 vs. manual 20, P = 0.625; right coronary artery: automatic 33 vs. manual 31, P = 0.500). At the patient's level, there was no statistic difference existed in the classification of Agatston scoring (P = 0.317) and the number of calcified vessels (P = 0.102) between the automatic and manual results.

conclusionsThe proposed framework can achieve reliable and comprehensive quantification for the CACS, including the calcified extent and distribution indicators at both total and vessel-specific levels.

Indexed as

Coronary Artery DiseaseVascular CalcificationCalciumCoronary AngiographyCoronary VesselsHumansRetrospective StudiesTomography, X-Ray ComputedCalciumCalciumCoronary artery diseaseDeep learningTomographyX-ray computed

Identifiers

PMID33302029
PMCPMC7814341

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