ArticlePest management science2021
Widespread multiple insecticide resistance in the major dengue vector Aedes albopictus in Hainan Province, China.
Article in Pest management science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 60 citations in OpenAlex.
- Research Trends and Collaborative Patterns inInternational journal of environmental research and public health · 2026Article
- Emerging and regionally novel voltage-gated sodium channel mutations associated with pyrethroid resistance and altered binding affinity in Aedes albopictus (Skuse) from Northern Peninsular Malaysia.Parasites & vectors · 2026Article
- Larval competition between the invasive Anopheles stephensi and African native mosquitoes.Research square · 2026Article
- Aedes albopictus gut symbiotic bacterium Bacillus cereus improves its deltamethrin resistance.Parasites & vectors · 2026Article
- Integrated transcriptome-microbiome analysis reveals a host-microbe interplay associated with insecticide resistance inFrontiers in microbiology · 2026Article
- F1534SFrontiers in cellular and infection microbiology · 2026Article
- Detection of insecticide resistance and knockdown resistance (Frontiers in cellular and infection microbiology · 2026Article
- Progress in research on mosquito-borne viruses: Understanding infection, transmission, and control.Infectious diseases & immunity · 2026Review
- Insecticide resistance levels, spatial distribution, and kdr mutations in the dengue vector Aedes albopictus of Hong Kong.PLoS neglected tropical diseases · 2025Article
- Mechanisms of pyrethroid resistance in Culicidae mosquitoes from Hainan Island, China.Parasites & vectors · 2025Article
- Omics Approaches in Understanding Insecticide Resistance in Mosquito Vectors.International journal of molecular sciences · 2025Review
- Distribution and frequency of genetic mutations in three insecticide targets in field populations ofFrontiers in cellular and infection microbiology · 2025Article
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- Article
- Mosquito Gut Microbiota: A Review.Pathogens (Basel, Switzerland) · 2024Review
- Unveiling candidate genes for metabolic resistance to malathion in Aedes albopictus through RNA sequencing-based transcriptome profiling.PLoS neglected tropical diseases · 2024Article
- Resistance to pyrethroids and the relationship between adult resistance and knockdown resistance (kdr) mutations in Aedes albopictus in dengue surveillance areas of Guizhou Province, China.Scientific reports · 2024Article
- Insecticide resistance in the field populations of the Asian tiger mosquitoFrontiers in physiology · 2024Article
- Article
- The dynamics of deltamethrin resistance evolution in Aedes albopictus has an impact on fitness and dengue virus type-2 vectorial capacity.BMC biology · 2023Article
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Authors and funding
12 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundAedes albopictus is a highly invasive mosquito and has become a potential vector of dengue, chikungunya and Zika viruses. Insecticide-based mosquito interventions are the main tools for vector-borne disease control. However, mosquito resistance to insecticides is a major threat to effective prevention and control. Five Ae. albopictus populations across Hainan Province, China were investigated for susceptibility to multiple insecticide and resistance mechanisms.
resultsLarval bioassays indicated that resistance to pyrethroids was common in all larval populations. Adult bioassays revealed all populations were either resistant or highly resistant to at least four of the six synthetic insecticides (deltamethrin, permethrin, cyfluthrin, propoxur, malathion, and DDT) tested. Pre-exposure of mosquitoes to the synergistic agent piperonyl butoxide (PBO) increased mosquito mortality by 2.4-43.3% in bioassays to DDT, malathion, and permethrin and rendered mosquito sensitive to deltamethrin, cyfluthrin, and propoxur. The frequency of knockdown resistance (kdr) mutations (F1534S and F1534C) ranged from 69.8% to 89.3% and from 38.1% to 87.0% in field-resistant and sensitive populations, respectively. F1534S mutation was significantly associated with pyrethroid resistance. No mutation was detected in the acetylcholinesterase (ace-1) gene in the two examined populations.
conclusionThis study provides evidence of widespread resistance to multiple insecticides in Ae. albopictus in Hainan Province, China. Both kdr mutations and metabolic detoxification were potential causes of insecticide resistance for Ae. albopictus. Our findings highlight the need for insecticide resistance management and mosquito control measures that do not entirely depend on synthetic insecticides. © 2020 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
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