Evidence map›Paper›PMID 33301369›Full record

ArticleExpert opinion on biological therapy2021

B7-H3 targeted antibody-based immunotherapy of malignant diseases.

Theodoros Michelakos, Filippos Kontos, Omar Barakat, Luke Maggs, Joseph H Schwab, Cristina R Ferrone, Soldano Ferrone

Open access · greenAbstract read
In one paragraph

Article in Expert opinion on biological therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 36 citations in OpenAlex.

  1. Development and Preclinical Evaluation ofJournal of medicinal chemistry · 2026
    Article
  2. B7-H3 CAR T cells eradicate intrahepatic cholangiocarcinoma and induce durable response.Journal of experimental & clinical cancer research : CR · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Theodoros MichelakosDepartment of Surgery, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-4047-0926
Filippos KontosDepartment of Surgery, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA.
Omar BarakatDepartment of Surgery, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA.
Luke MaggsDepartment of Surgery, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA.
Joseph H SchwabDepartment of Orthopaedic Surgery, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA.
Cristina R FerroneDepartment of Surgery, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA.
Soldano FerroneDepartment of Surgery, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA.
Harvard University · US

Funding

T cell plasticity, fusion proteins and CAR T cell-based immunotherapy of head and neck cancerR01DE028172 · NIDCR · MASSACHUSETTS GENERAL HOSPITAL · PI WANG, XINHUI · 2018 to 2022
$1.9M
IL-15 TRiKES-based specific immunotherapy of pancreatic ductal adenocarcinomaR03CA231766 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI FERRONE, CRISTINA R., FERRONE, SOLDANO · 2018 to 2019
$177k
Safety and anti-tumor activity of B7-H3 CAR T cells in TNBCR03CA223886 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI DOTTI, GIANPIETRO, FERRONE, SOLDANO · 2018 to 2019
$176k
B7-H3 CAR T cell-based immunotherapy combined with Losartan to counteract desmoplasia for the treatment of Pancreatic Ductal Adenocarcinoma (PDAC)R03CA249542 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI FERRONE, CRISTINA R., FERRONE, SOLDANO · 2021 to 2021
$167k
NCI NIH HHS R03 CA223886NCI NIH HHS R03 CA231766NCI NIH HHS R03 CA249542NIDCR NIH HHS R01 DE028172
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

B7 AntigensNeoplasmsAntibodies, MonoclonalAntigens, NeoplasmHumansImmunotherapyAntibodies, MonoclonalAntigens, NeoplasmB7 AntigensB7-H3immunotherapymonoclonal antibodytumor antigen

Identifiers

PMID33301369
PMCPMC8087627
OpenAlexW3110944345

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.