ArticleDer Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft2021
[Change of corneal radii after Descemet membrane endothelial keratoplasty measured by optical coherence tomography and Scheimpflug tomography].
Article in Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundThe aim of the study was to compare the measurement of corneal radii using Scheimpflug tomography (Pentacam®, Oculus, Wetzlar, Germany) and optical coherence tomography (OCT, Optovue® XR-Avanti, Fremont, CA, USA) in eyes of patients with Fuchs' endothelial dystrophy (FED) before and after Descemet membrane endothelial keratoplasty (DMEK). MATERIAL AND
methodsIn a retrospective analysis 35 eyes with (FED) that underwent DMEK were included. Pentacam® and Optovue® corneal measurements were performed preoperatively and at least 3 months postoperatively. The four primary objectives were the radii of the anterior and posterior corneal surfaces, the corneal thickness and the posterior to anterior corneal curvature radii ratio. The change in the primary targets after DMEK was analyzed and the measurement results of both methods were compared. A Bland-Altman plot was created to graphically illustrate the correlation between the two measuring methods.
resultsA significant decrease in corneal thickness was observed after DMEK with both methods. The radii of the anterior corneal surface, measured with Scheimpflug as well as with OCT showed no significant changes after surgery, while the radii of the posterior corneal surface significantly decreased (Pentacam®: preoperative = 7.24 mm ± 0.99 mm; postoperative = 6.38 mm ± 0.40 mm, P < 0.001; Optovue®: preoperative = 7.63 mm ± 1.43 mm; postoperative = 6.57 mm ± 0.43 mm, P < 0.001). The Bland-Altman plots of all primary objectives showed a better agreement postoperatively compared to the preoperative measurements.
conclusionBoth Scheimpflug and OCT showed a significant decrease in the radius of the posterior corneal surface after DMEK. The postoperative measurements showed a higher agreement between the devices than those performed preoperatively.
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