Evidence map›Paper›PMID 33301052›Full record

ArticleClinical neuroradiology2021

Mechanical Thrombectomy for Acute Intracranial Carotid Occlusion with Patent Intracranial Arteries : The Italian Registry of Endovascular Treatment in Acute Stroke.

Fabrizio Sallustio, Valentina Saia, Federico Marrama, Giovanni Pracucci, Roberto Gandini, Giacomo Koch, Alfredo Paolo Mascolo, Federica D'Agostino, Alessandro Rocco, Renato Argiro' and 78 more

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Article in Clinical neuroradiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

88 authors at 20 institutions in 1 country.

Fabrizio SallustioStroke Unit, Department of Systems Medicine, University of Tor Vergata, Viale Oxford 81, 00133, Rome, Italy. fsall75@gmail.com.ORCID http://orcid.org/0000-0002-8229-465X
Valentina SaiaNeurology and Stroke Unit, Santa Corona Hospital, Pietra Ligure, Italy.
Federico MarramaStroke Unit, Department of Systems Medicine, University of Tor Vergata, Viale Oxford 81, 00133, Rome, Italy.
Giovanni PracucciStroke Unit, Ospedale Careggi-University Hospital, Firenze, Italy.
Roberto GandiniInterventional Radiology Unit, Department of Biomedicine and Prevention, University of Tor Vergata, Rome, Italy.
Giacomo KochStroke Unit, Department of Systems Medicine, University of Tor Vergata, Viale Oxford 81, 00133, Rome, Italy.
Alfredo Paolo MascoloStroke Unit, Department of Systems Medicine, University of Tor Vergata, Viale Oxford 81, 00133, Rome, Italy.
Federica D'AgostinoStroke Unit, Department of Systems Medicine, University of Tor Vergata, Viale Oxford 81, 00133, Rome, Italy.
Alessandro RoccoStroke Unit, Department of Systems Medicine, University of Tor Vergata, Viale Oxford 81, 00133, Rome, Italy.
Renato Argiro'Interventional Radiology Unit, Department of Biomedicine and Prevention, University of Tor Vergata, Rome, Italy.
Marco NezzoInterventional Radiology Unit, Department of Biomedicine and Prevention, University of Tor Vergata, Rome, Italy.
Daniele MorosettiInterventional Radiology Unit, Department of Biomedicine and Prevention, University of Tor Vergata, Rome, Italy.
Andrea WlderkInterventional Radiology Unit, Department of Biomedicine and Prevention, University of Tor Vergata, Rome, Italy.
Valerio Da RosInterventional Radiology Unit, Department of Biomedicine and Prevention, University of Tor Vergata, Rome, Italy.
Marina DiomediStroke Unit, Department of Systems Medicine, University of Tor Vergata, Viale Oxford 81, 00133, Rome, Italy.
Leonardo RenieriInterventional Neuroradiology Unit, Ospedale Careggi-University Hospital, Firenze, Italy.
Patrizia NenciniStroke Unit, Ospedale Careggi-University Hospital, Firenze, Italy.
Stefano ValloneNeuroradiology Unit, Ospedale Civile S. Agostino-Estense University Hospital, Modena, Italy.
Andrea ZiniIRCCS Istituto di Scienze Neurologiche di Bologna, Department of Neurology and Stroke Center, Maggiore Hospital, Bologna, Italy.
Guido BigliardiNeuroradiology Unit, Ospedale Civile S. Agostino-Estense University Hospital, Modena, Italy.
Antonio CaraglianoInterventional Neuroradiology Unit, Policlinico G. Martino, Messina, Italy.
Isabella FrancalanzaStroke Unit, Policlinico G. Martino, Messina, Italy.
Sandra BraccoInterventional Neuroradiology Unit, Ospedale S. Maria delle Scotte-University Hospital, Siena, Italy.
Rossana TassiStroke Unit, Ospedale S. Maria delle Scotte-University Hospital, Siena, Italy.
Mauro BerguiInterventional Neuroradiology Unit, Città della Salute e della Scienza-Molinette, Torino, Italy.
Andrea NaldiStroke Unit, Città della Salute e della Scienza-Molinette, Torino, Italy.
Andrea SalettiInterventional Neuroradiology Unit, Arcispedale S. Anna-University Hospital, Ferrara, Italy.
Alessandro De VitoNeurology Division and Stroke Unit, Arcispedale S. Anna-University Hospital, Ferrara, Italy.
Roberto GasparottiNeuroradiology Unit, Spedali Civili, Brescia, Italy.
Mauro MagoniStroke Unit, Spedali Civili, Brescia, Italy.
Luigi CirilloIRCCS Istituto di Scienze Neurologiche di Bologna, Neuroradiology Unit, Ospedale Bellaria, Bologna University-DIMES, Bologna, Italy.
Christian CommodaroInterventional Neuroradiology Unit, AUSL Romagna Cesena, Cesena, Italy.
Sara BiguzziNeurology and Stroke Unit, AUSL Romagna Cesena, Cesena, Italy.
Lucio CastellanInterventional Neuroradiology Unit, IRCCS San Martino-IST, Genova, Italy.
Laura MalfattoStroke Unit, IRCCS San Martino-IST, Genova, Italy.
Roberto MenozziInterventional Neuroradiology Unit, Ospedale Universitario, Parma, Italy.
Ilaria GrisendiStroke Unit, Ospedale Universitario, Parma, Italy.
Mirco CosottiniDepartment of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Giovanni OrlandiDepartment of Clinical and Experimental Medicine, Neurological Institute, University of Pisa, Pisa, Italy.
Alessio ComaiRadiology Unit, Ospedale Centrale, Bolzano, Italy.
Enrica FranchiniStroke Unit, Ospedale Centrale, Bolzano, Italy.
Francesco D'ArgentoInterventional Radiology Unit, Fondazione Policlinico Gemelli, Roma, Italy.
Giovanni FrisulloStroke Unit, Fondazione Policlinico Gemelli, Roma, Italy.
Edoardo PuglielliInterventional Radiology Unit, Ospedale Civile Mazzini, Teramo, Italy.
Alfonsina CasalenaNeurology Unit, Ospedale Civile Mazzini, Teramo, Italy.
Francesco CausinNeuroradiology Unit, Azienda Ospedaliero-Universitaria, Padova, Italy.
Claudio BaracchiniStroke Unit, Azienda Ospedaliero-Universitaria, Padova, Italy.
Andrea BoghiInterventional Neuroradiology Unit, Ospedale San Giovanni Bosco, Torino, Italy.
Gigliola ChianaleNeurology Unit, Ospedale San Giovanni Bosco, Torino, Italy.
Raffaele AugelliNeuroradiology Unit, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.
Manuel CappellariStroke Unit, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.
Luigi ChiumaruloInterventional Neuroradiology Unit, AOU Consorziale Policlinico, Bari, Italy.
Marco PetruzzellisNeurology and Stroke Unit, AOU Consorziale Policlinico, Bari, Italy.
Alessandro SgrecciaDiagnostic Radiology and Interventional Neuroradiology, IRCCS Policlinico San Matteo, Pavia, Italy.
Piera TosiCerebrovascular Disease and Stroke Unit, IRCCS Fondazione Mondino, Pavia, Italy.
Nicola CavasinNeuroradiology Unit, Ospedale dell'Angelo, USSL3 Serenissima, Mestre, Italy.
Adriana CritelliNeurology Unit, Ospedale dell'Angelo, USSL3 Serenissima, Mestre, Italy.
Vittorio SemeraroNeuroradiology Unit, Osp. "SS. Annunziata"-ASL TA, Taranto, Italy.
Giovanni BoeroNeurology Unit, Osp. "SS. Annunziata"-ASL TA, Taranto, Italy.
Francesco VizzariNeuroradiology Department, Ospedale di Circolo di Varese, ASST-Sette Laghi, Varese, Italy.
Lucia Princiotta CariddiNeurology and Stroke Unit, Ospedale di Circolo di Varese, ASST-Sette Laghi, Varese, Italy.
Olindo Di BenedettoNeuroradiology Unit, Azienda Ospedaliera Cosenza, Cosenza, Italy.
Pierfrancesco PuglieseStroke Unit, Azienda Ospedaliera Cosenza, Cosenza, Italy.
Marta IacobucciInterventional Neuroradiology Unit, University of Rome La Sapienza, Roma, Italy.
Manuela De MicheleStroke Unit, University of Rome La Sapienza, Roma, Italy.
Federico FusaroInterventional Neuroradiology, Azienda Ospedaliera Brotzu, Cagliari, Italy.
Jessica MollerStroke Unit, Azienda Ospedaliera Brotzu, Cagliari, Italy.
Luca AllegrettiNeuroradiology Unit, Santa Corona Hospital, Pietra Ligure, Italy.
Tiziana TassinariNeurology and Stroke Unit, Santa Corona Hospital, Pietra Ligure, Italy.
Nunzio Paolo NuzziNeuroradiology Unit, IRCCS Humanitas Rozzano, Rozzano, Milano, Italy.
Simona MarcheselliStroke Unit, IRCCS Humanitas Rozzano, Rozzano, Milano, Italy.
Simona SaccoDepartment of Clinical Sciences and Biotechnology, University of L'Aquila, Avezzano, L'Aquila, Italy.
Marco PaviaNeuroradiology Unit, Fondazione Poliambulanza, Brescia, Italy.
Paolo InvernizziStroke Unit, Fondazione Poliambulanza, Brescia, Italy.
Ivan GallesioNeuroradiology Unit, Azienda Ospedaliera "SS Antonio e Biagio e C. Arrigo", Alessandria, Italy.
Luigi RuizNeurology Department, Azienda Ospedaliera "SS Antonio e Biagio e C. Arrigo", Alessandria, Italy.
Sandro ZeddaInterventional Radiology, Ospedale San Francesco, Nuoro, Italy.
Rosario RossiNeurology and Stroke Unit, Ospedale San Francesco, Nuoro, Italy.
Pietro AmistàNeuroradiology Unit, Ospedale S. Maria Misericordia, Rovigo, Italy.
Monia RussoStroke Unit, Ospedale S. Maria Misericordia, Rovigo, Italy.
Francesco PintusNeuroradiology Unit, Ospedale SS Annunziata, Sassari, Italy.
Alessandra SannaStroke Unit, Ospedale SS Annunziata, Sassari, Italy.
Giuseppe CraparoInterventional Radiology, Ospedale Civico e Benfratelli, Palermo, Italy.
Marina ManninoNeurology Unit, Ospedale Civico e Benfratelli, Palermo, Italy.
Domenico InzitariStroke Unit, Ospedale Careggi-University Hospital, Firenze, Italy.
Salvatore MangiaficoInterventional Neuroradiology Unit, Ospedale Careggi-University Hospital, Firenze, Italy.
Danilo ToniStroke Unit, University of Rome La Sapienza, Roma, Italy.
Italian Registry of Endovascular Treatment in Acute Stroke (IRETAS) Collaborators
University of Rome Tor Vergata · ITAzienda Ospedaliero-Universitaria Careggi · ITAzienda Unita' Sanitaria Locale Di Modena · ITAgostino Gemelli University Polyclinic · ITAzienda Ospedaliera Citta' della Salute e della Scienza di Torino · ITAzienda Ospedaliera di Cosenza · ITAzienda Ospedaliera Universitaria Integrata Verona · ITAzienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · ITOspedale Santa Maria della Misericordia di Rovigo · ITOspedale SS. Annunziata · ITUniversity of Pisa · ITAzienda di Rilievo Nazionale ed Alta Specializzazione · ITAzienda Ospedale - Università Padova · ITAzienda Ospedaliera G. Brotzu · ITAzienda Ospedaliera Nazionale SS. Antonio e Biagio e Cesare Arrigo · ITAzienda-Unita' Sanitaria Locale Di Cesena · ITFondazione FADOI · ITFondazione Poliambulanza Istituto Ospedaliero · ITIRCCS Humanitas Research Hospital · ITOspedale dell' Angelo · IT

Funding

Italian Ministry of Health RFPS-2006-1-336562
6 · The paper itself

Abstract

purposeIntracranial carotid artery occlusion represents an underinvestigated cause of acute ischemic stroke as well as an indication for mechanical thrombectomy. We investigated baseline and procedural characteristics, outcomes and predictors of outcome in patients with acute ischemic stroke secondary to intracranial carotid artery occlusion.

methodsA retrospective analysis of the Italian Registry of Endovascular Treatment in Acute Stroke was performed. Patients with intracranial carotid artery occlusion (infraclinoid and supraclinoid) with or without cervical artery occlusion but with patent intracranial arteries were included. The 3‑month functional independence, mortality, successful reperfusion and symptomatic intracranial hemorrhage were evaluated.

resultsIntracranial carotid artery occlusion with patent intracranial arteries was diagnosed in 387 out of 4940 (7.8%) patients. The median age was 74 years and median baseline National Institute of Health Stroke Scale (NIHSS) was 18. Functional independence was achieved in 130 (34%) patients, successful reperfusion in 289 (75%) and symptomatic intracranial hemorrhage in 33 (9%), whereas mortality occurred in 111 (29%) patients. In univariate analysis functional independence was associated with lower age, lower NIHSS at presentation, higher rate of successful reperfusion and lower rate of symptomatic intracranial hemorrhage. Multivariable regression analysis found age (odds ratio, OR:1.03; P = 0.006), NIHSS at presentation (OR: 1.07; P < 0.001), diabetes (OR: 2.60; P = 0.002), successful reperfusion (OR:0.20; P < 0.001) and symptomatic intracranial hemorrhage (OR: 4.17; P < 0.001) as the best independent predictors of outcome.

conclusionOur study showed a not negligible rate of intracranial carotid artery occlusion with patent intracranial arteries, presenting mostly as severe stroke, with an acceptable rate of 3‑month functional independence. Age, NIHSS at presentation and successful reperfusion were the best independent predictors of outcome.

Indexed as

Brain IschemiaEndovascular ProceduresStrokeThrombectomyAgedCarotid ArteriesHumansItalyRegistriesRetrospective StudiesTreatment OutcomeCircle of WillisEndovascular treatmentLarge vessel occlusionOutcomeStroke severity

Identifiers

PMID33301052
OpenAlexW3113218182

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