Evidence map›Paper›PMID 33300963›Full record

ArticleAmerican journal of clinical pathology2021

Strengthening Laboratory Diagnostic Capacity to Support Cancer Care in Uganda.

Nixon Niyonzima, Henry Wannume, Sylivestor Kadhumbula, Hassan Wasswa, Godfrey Osinde, Yusuf Mulumba, Tobias Tusabe, Samuel Kalungi, Jackson Orem

Open access · bronzeAbstract read
In one paragraph

Article in American journal of clinical pathology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Nixon NiyonzimaUganda Cancer Institute, Kampala, Uganda.ORCID 0000-0001-7489-6813
Henry WannumeUganda Cancer Institute, Kampala, Uganda.
Sylivestor KadhumbulaUganda Cancer Institute, Kampala, Uganda.
Hassan WasswaUganda Cancer Institute, Kampala, Uganda.
Godfrey OsindeUganda Cancer Institute, Kampala, Uganda.
Yusuf MulumbaUganda Cancer Institute, Kampala, Uganda.
Tobias TusabeUganda Cancer Institute, Kampala, Uganda.
Samuel KalungiDepartment of Pathology, School of Biomedical Sciences, College of Health Sciences, Makerere University, Kampala, Uganda.
Jackson OremUganda Cancer Institute, Kampala, Uganda.
Uganda Cancer Institute · UGFred Hutch Cancer Center · USMbarara University of Science and Technology · UGMulago Hospital · UG

Funding

Expanding independent research capacity in HIV-associated malignancies in UgandaD43TW009759 · FIC · FRED HUTCHINSON CANCER RESEARCH CENTER · PI OREM, JACKSON, PHIPPS, WARREN · 2014 to 2023
$3.0M
FIC NIH HHS D43 TW009759
6 · The paper itself

Abstract

objectivesAn accurate cancer diagnosis is critical to providing quality care to patients with cancer. We describe the results of a laboratory improvement process that started in 2017 to improve access to cancer diagnostics at the Uganda Cancer Institute (UCI). The overall objective of the project was to build capacity for the provision of quality and timely laboratory diagnostics to support cancer care in Uganda.

methodsA phased multistep approach was used to improve laboratory capacity, including staff training, additional staff recruitment, equipment overhaul, and optimization of the supply chain.

resultsThe program led to the establishment of a pathology laboratory that handled 5,700 tissue diagnoses in 2019. Immunohistochemistry services are now offered routinely. Turnaround time for histopathology has also reduced from an average of 7 to 14 days to 5.4 days. The main clinical laboratory has also increased both the test volume and the test capacity, with the additional establishment of a molecular diagnostics laboratory.

conclusionsOur project shows a pathway to the improvement of laboratory diagnostic capacity in cancer care centers in sub-Saharan Africa (SSA). Improved laboratory diagnostic capacity is critical to improving cancer care in SSA and more rational use of targeted therapies.

Indexed as

LaboratoriesPathology, ClinicalQuality Assurance, Health CareHumansNeoplasmsUgandaCancer diagnosisCapacity buildingLaboratoryPathologySub-Saharan Africa

Identifiers

PMID33300963
PMCPMC8859427
OpenAlexW3111670060

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.