Evidence map›Paper›PMID 33300872›Full record

ArticleeLife2020

Epidermal PAR-6 and PKC-3 are essential for larval development of

Victoria G Castiglioni, Helena R Pires, Rodrigo Rosas Bertolini, Amalia Riga, Jana Kerver, Mike Boxem

Open access · goldAbstract readVideo-Audio Media
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 39 citations in OpenAlex.

  1. Review
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  3. LGL-1 and the RhoGAP protein PAC-1 redundantly polarize thebioRxiv : the preprint server for biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Victoria G Castiglioni *Division of Developmental Biology, Institute of Biodynamics and Biocomplexity, Department of Biology, Faculty of Science, Utrecht University, Utrecht, Netherlands.ORCID 0000-0001-9884-2537
Helena R Pires *Division of Developmental Biology, Institute of Biodynamics and Biocomplexity, Department of Biology, Faculty of Science, Utrecht University, Utrecht, Netherlands.ORCID 0000-0001-8351-0812
Rodrigo Rosas BertoliniDivision of Developmental Biology, Institute of Biodynamics and Biocomplexity, Department of Biology, Faculty of Science, Utrecht University, Utrecht, Netherlands.
Amalia RigaDivision of Developmental Biology, Institute of Biodynamics and Biocomplexity, Department of Biology, Faculty of Science, Utrecht University, Utrecht, Netherlands.
Jana KerverDivision of Developmental Biology, Institute of Biodynamics and Biocomplexity, Department of Biology, Faculty of Science, Utrecht University, Utrecht, Netherlands.
Mike BoxemDivision of Developmental Biology, Institute of Biodynamics and Biocomplexity, Department of Biology, Faculty of Science, Utrecht University, Utrecht, Netherlands.ORCID 0000-0003-3966-4173
Utrecht University · NL

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
H2020 Marie Skłodowska-Curie Actions ITN 675407Nederlandse Organisatie voor Wetenschappelijk Onderzoek 016.VICI.170.165Nederlandse Organisatie voor Wetenschappelijk Onderzoek 824.14.021NIH HHS P40 OD010440
6 · The paper itself

Abstract

The cortical polarity regulators PAR-6, PKC-3, and PAR-3 are essential for the polarization of a broad variety of cell types in multicellular animals. In

Indexed as

AnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsCell DivisionEpidermisLarvaMicrotubulesProtein Kinase CCaenorhabditis elegans Proteinspar-6 protein, C elegansPKC-3 proteinProtein Kinase CaPKCC. eleganscell biologycell polaritydevelopmental biologymicrotubuleNOCA-1Par3Par6

Identifiers

PMID33300872
PMCPMC7755398
OpenAlexW3111489121

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.