Evidence map›Paper›PMID 33300871›Full record

ArticleeLife2020

A positive feedback loop between Flower and PI(4,5)P

Tsai-Ning Li, Yu-Jung Chen, Ting-Yi Lu, You-Tung Wang, Hsin-Chieh Lin, Chi-Kuang Yao

Abstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. The human Flower isoform hFWE4 facilitates cornification in cutaneous squamous cell carcinoma.JID innovations : skin science from molecules to population health · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tsai-Ning LiInstitute of Biological Chemistry, Academia Sinica, Taipei, Taiwan.ORCID 0000-0003-0195-145X
Yu-Jung ChenInstitute of Biological Chemistry, Academia Sinica, Taipei, Taiwan.
Ting-Yi LuInstitute of Biological Chemistry, Academia Sinica, Taipei, Taiwan.
You-Tung WangInstitute of Biological Chemistry, Academia Sinica, Taipei, Taiwan.
Hsin-Chieh LinInstitute of Biological Chemistry, Academia Sinica, Taipei, Taiwan.
Chi-Kuang YaoInstitute of Biological Chemistry, Academia Sinica, Taipei, Taiwan.ORCID 0000-0003-0977-4347

Funding

Ministry of Science and Technology, Taiwan 106-0210-01-15-02Ministry of Science and Technology, Taiwan 107-0210-01-19-01Ministry of Science and Technology, Taiwan 107-2311-B-001-003-MY3
6 · The paper itself

Abstract

Synaptic vesicle (SV) endocytosis is coupled to exocytosis to maintain SV pool size and thus neurotransmitter release. Intense stimulation induces activity-dependent bulk endocytosis (ADBE) to recapture large quantities of SV constituents in large endosomes from which SVs reform. How these consecutive processes are spatiotemporally coordinated remains unknown. Here, we show that Flower Ca

Indexed as

AnimalsCalcium ChannelsDrosophilaDrosophila ProteinsEndocytosisFeedback, PhysiologicalNeuromuscular JunctionPhosphatidylinositol PhosphatesPresynaptic TerminalsSynaptic TransmissionSynaptic VesiclesCalcium ChannelsDrosophila Proteinsfwe protein, DrosophilaPhosphatidylinositol Phosphatesbulk endocytosisCa2+ channelD. melanogasterneuroscienceperiactive zonePIP2synaptic vesicle endocytosis

Identifiers

PMID33300871
PMCPMC7748424

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.