ArticleClinical and experimental dental research2021
Prediabetes/diabetes screening strategy at the periodontal clinic.
Article in Clinical and experimental dental research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The trial behind it
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Who cites it
27 citing papers in PubMed.
- Dual-Biomarker Oral-Rinse Testing for aMMP-8 and Calprotectin: A Potential Adjunctive Tool for Risk Stratification and Interdisciplinary Referral in Periodontitis and Type 2 Diabetes.Bioengineering (Basel, Switzerland) · 2026Review
- Diagnostic Potential of aMMP-8 PoCT in Oral Fluids: Insights from Periodontitis and Metabolic Syndrome Interplay.European journal of dentistry · 2026Article
- From biological evidence to clinical application: a scoping review of oral fluid biomarkers in type 2 diabetic periodontitis.Frontiers in oral health · 2026Review
- Salivary biomarker profiling in prediabetes-associated periodontitis: role of adiponectin, resistin, and total matrix metalloproteinase-8.Frontiers in dental medicine · 2026Article
- Statistical Method for Dental Clinics for Determining Presence and Stage of Periodontitis with aMMP-8 Mouth Rinse Point-of-Care Test and Digital Reader.Dentistry journal · 2025Article
- Diagnostic accuracy of aMMP-8 levels in oral biofluids for monitoring periodontitis in patients with metabolic syndrome.Clinical oral investigations · 2025Article
- Salivary advanced glycated end products, their receptors, and aMMP-8 in periodontitis patients with varying glycemic levels: A cross-sectional study.Journal of periodontology · 2025Article
- Determination of the Stage of Periodontitis with 20 ng/mL Cut-Off aMMP-8 Mouth Rinse Test and Polynomial Functions in a Mobile Application.Diagnostics (Basel, Switzerland) · 2025Article
- Prediabetes Associates with Matrix Metalloproteinase-8 Activation and Contributes to the Rapid Destruction of Periodontal Tissues.European journal of dentistry · 2025Article
- Article
- Periodontitis Home Screening with Mouth Rinse Cut-Off 20 Ng/mL aMMP-8 Test and Mobile Application.Diagnostics (Basel, Switzerland) · 2025Article
- Leveraging Dental Visits for Systemic Health: Diabetes Screening and Referral Compliance in Periodontitis Patients in Malaysia.Journal of clinical medicine · 2025Article
- Applicability of an active matrix metalloproteinase-8 point-of-care test in an oral and maxillofacial surgery clinic: a pilot study.Odontology · 2024Article
- Supplementary Effects ofPharmaceuticals (Basel, Switzerland) · 2023Article
- aMMP-8 Point-of-Care Test (POCT) Identifies Reliably Periodontitis in Patients with Type 2 Diabetes as well as Monitors Treatment Response.Diagnostics (Basel, Switzerland) · 2023Article
- Article
- Oral health professionals screening for undiagnosed type-2 diabetes and prediabetes: the iDENTify study.BMC endocrine disorders · 2022Article
- Is There a Link between COVID-19 and Periodontal Disease? A Narrative Review.European journal of dentistry · 2022Article
- Active MMP-8 point-of-care (PoC)/chairside enzyme-test as an adjunctive tool for early and real-time diagnosis of peri-implantitis.Clinical and experimental dental research · 2022Article
- Active matrix metalloproteinase-8: A potential biomarker of oral systemic link.Clinical and experimental dental research · 2022Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of the study was to propose an efficient chairside clinical strategy for the identification of undiagnosed hyperglycaemia in periodontal clinics. MATERIAL AND
methodsΑ chairside system was used for assessment of glycated hemoglobin 1c (HbA1c) and active Matrix Metalloproteinase-8 levels (aMMP-8) were analyzed by immunotest in patients (n = 150) who fulfilled the criteria for screening of the Centers for Disease Control and Prevention. Full-mouth periodontal parameters were assessed and various data such as Body Mass Index (BMI), smoking and education were recorded.
resultsThirty-one patients out of 150 tested were found with unknown hyperglycaemia (20.7%). Regarding sex, education, parent with diabetes, normal BMI, smoking, age ≥45 years and prior testing for diabetes, no differences were observed between subjects displaying HbA1c < 5.7 and ≥5.7% (Pearson's Chi-square test, p > .05). Subgroups differed regarding BMI (kg/m
conclusionsFindings of the study suggest that the combination of stage of periodontitis, increasing age, BMI and aMMP-8, without chairside HbA1c assessment appears to be a viable screening strategy for referring dental patients for testing for prediabetes/diabetes.
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