Evidence map›Paper›PMID 33300399›Full record

ArticleThe International journal of artificial organs2021

Real-time, non-invasive thrombus detection in an extracorporeal circuit using micro-optical thrombus sensors.

Nobutomo Morita, Daisuke Sakota, Akiko Oota-Ishigaki, Ryo Kosaka, Osamu Maruyama, Masahiro Nishida, Kazuki Kondo, Toshihiro Takeshita, Wataru Iwasaki

Open access · bronzeAbstract read
In one paragraph

Article in The International journal of artificial organs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. A Novel Method for Predicting Recirculation by Sweep-Gas Control in Extracorporeal Membrane Oxygenation.Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Nobutomo MoritaSensing System Research Center, National Institute of Advanced Industrial Science and Technology (AIST), Tosu, Saga, Japan.ORCID https://orcid.org/0000-0002-5075-3209
Daisuke SakotaHealth and Medical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki, Japan.
Akiko Oota-IshigakiHealth and Medical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki, Japan.
Ryo KosakaHealth and Medical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki, Japan.
Osamu MaruyamaHealth and Medical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki, Japan.
Masahiro NishidaHealth and Medical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki, Japan.
Kazuki KondoHealth and Medical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki, Japan.
Toshihiro TakeshitaSensing System Research Center, National Institute of Advanced Industrial Science and Technology (AIST), Tosu, Saga, Japan.
Wataru IwasakiSensing System Research Center, National Institute of Advanced Industrial Science and Technology (AIST), Tosu, Saga, Japan.
National Institute of Advanced Industrial Science and Technology · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionReal-time, non-invasive monitoring of thrombus formation in extracorporeal circuits has yet to be achieved. To address the challenges of conventional optical thrombus detection methods requiring large devices that limit detection capacity, we developed a micro-optical thrombus sensor.

methodsThe proposed micro-optical thrombus sensor can detect the intensity of light scattered by blood at wavelengths of 660 and 855 nm. Two thrombus sensors were installed on in vitro circuit: one at the rotary blood pump and one at a flow channel. To evaluate the variation in the ratio of incident light intensity at each wavelength of the two sensors,

resultsIn all three thrombus detection tests,

conclusionThrombus detection in an extracorporeal circuit using the developed micro-optical sensors was successfully demonstrated in an in vitro test.

Indexed as

ThrombosisAnimalsHematocritSwineanticoagulation managementblood monitoringMicro-optical sensorreal-time detectionthrombus monitoring

Identifiers

PMID33300399
PMCPMC8366175
OpenAlexW3113217196

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.