ArticleiScience2020
Membrane Estrogen Receptor (GPER) and Follicle-Stimulating Hormone Receptor (FSHR) Heteromeric Complexes Promote Human Ovarian Follicle Survival.
2 registry-linked trialsOpen access · goldAbstract read
In one paragraph
Article in iScience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 33 papers.
0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
4.9field-weighted citation impact, top 5% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Autologous Adipose Tissue Harvested With Superficial Enhanced Fluid Fat Injection (SEFFICARE) Method for Treatment of Diabetic Foot Ulcer Undergoing Minor Amputation (SEFFIDiFA): Proposal of Basic Research and Prospective Observational Study
Identification of Genetic Targets in Gynecological Tumors Via a Triple in Silico Ex-vivo / in Vivo Approach
Who cites it
33 citing papers in PubMed, 55 citations in OpenAlex.
- Integrative Transcriptomic and Metabolomic Analysis Reveal Mechanisms Underlying Differential Fecundity in Yangtze River Delta White Goat.Animals : an open access journal from MDPI · 2026Article
- LHCGR phamacodynamic effects during follicular maturation.Frontiers in endocrinology · 2026Review
- The impact of genetic variants in folliculogenesis and steroidogenesis pathways on ovarian response: a post hoc multicenter multiethnic cohort study.Journal of assisted reproduction and genetics · 2025Article
- Stabilized DNature communications · 2025Article
- Targeted destruction of follicle stimulating hormone receptor-positive cancer cells in vitro and in vivo by a lytic peptide Phor21-FSHβ conjugate.Molecular medicine (Cambridge, Mass.) · 2025Article
- Single-molecule localization microscopy as a tool to quantify di/oligomerization of receptor tyrosine kinases and G protein-coupled receptors.Molecular pharmacology · 2025Review
- Pharmacogenomic of LH and its receptor: are we ready for clinical practice?Reproductive biology and endocrinology : RB&E · 2025Review
- Interaction of GPER-1 with the endocrine signaling axis in breast cancer.Frontiers in endocrinology · 2025Review
- Significance ofInternational journal of reproductive biomedicine · 2024Article
- G protein-coupled estrogen receptor (GPER)/GPR30 forms a complex with the βArchives of biochemistry and biophysics · 2024Article
- Benzo[a]pyrene disrupts LH/hCG-dependent mouse Leydig cell steroidogenesis through receptor/Gαs protein targeting.Scientific reports · 2024Article
- Article
- Differential effects of follicle-stimulating hormone glycoforms on the transcriptome profile of cultured rat granulosa cells as disclosed by RNA-seq.bioRxiv : the preprint server for biology · 2023Article
- Review
- Short-Term Exposure to Bisphenol A Does Not Impact Gonadal Cell Steroidogenesis In Vitro.Cells · 2023Article
- Biological Assay to Determine Gonadotropin Potency: From In Vivo to In Vitro Sustainable Method.International journal of molecular sciences · 2023Article
- Study of the Sensing Kinetics of G Protein-Coupled Estrogen Receptor Sensors for Common Estrogens and Estrogen Analogs.Molecules (Basel, Switzerland) · 2023Article
- Article
- Allosteric modulation of gonadotropin receptors.Frontiers in endocrinology · 2023Review
- Comparative G-Protein-Coupled Estrogen Receptor (GPER) Systems in Diabetic and Cancer Conditions: A Review.Molecules (Basel, Switzerland) · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
26 authors at 12 institutions in 5 countries.
Livio CasariniUnit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Ospedale Civile Sant'Agostino-Estense, Via P. Giardini 1355, 41126 Modena, Italy.
Clara LazzarettiUnit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Ospedale Civile Sant'Agostino-Estense, Via P. Giardini 1355, 41126 Modena, Italy.
Elia ParadisoUnit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Ospedale Civile Sant'Agostino-Estense, Via P. Giardini 1355, 41126 Modena, Italy.
Silvia LimoncellaUnit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Ospedale Civile Sant'Agostino-Estense, Via P. Giardini 1355, 41126 Modena, Italy.
Laura RiccettiUnit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Ospedale Civile Sant'Agostino-Estense, Via P. Giardini 1355, 41126 Modena, Italy.
Samantha SperdutiUnit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Ospedale Civile Sant'Agostino-Estense, Via P. Giardini 1355, 41126 Modena, Italy.
Beatrice MelliUnit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Ospedale Civile Sant'Agostino-Estense, Via P. Giardini 1355, 41126 Modena, Italy.
Serena MarcozziHistology and Embryology Section, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy.
Claudia AnzivinoUnit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Ospedale Civile Sant'Agostino-Estense, Via P. Giardini 1355, 41126 Modena, Italy.
Niamh S SayersInstitute of Reproductive and Developmental Biology, Imperial College London, London, UK.
Jakub CzapinskiDepartment of Biochemistry and Molecular Biology, Medical University of Lublin, Lublin, Poland.
Giulia BriganteUnit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Ospedale Civile Sant'Agostino-Estense, Via P. Giardini 1355, 41126 Modena, Italy.
Francesco PotìDepartment of Medicine and Surgery, Unit of Neurosciences, University of Parma, Parma, Italy.
Antonio La MarcaMother-Infant Department, University of Modena and Reggio Emilia, Modena, Italy.
Francesco De PascaliPRC, INRAE, CNRS, IFCE, Université de Tours, Nouzilly, France.
Eric ReiterPRC, INRAE, CNRS, IFCE, Université de Tours, Nouzilly, France.
Angela FalboDepartment of Obstetrics and Gynaecology, Fertility Center, ASMN. Azienda Unità Sanitaria Locale - IRCCS di Reggio Emilia, Reggio Emilia, Modena, Italy.
Jessica DaolioDepartment of Obstetrics and Gynaecology, Fertility Center, ASMN. Azienda Unità Sanitaria Locale - IRCCS di Reggio Emilia, Reggio Emilia, Modena, Italy.
Maria Teresa VillaniDepartment of Obstetrics and Gynaecology, Fertility Center, ASMN. Azienda Unità Sanitaria Locale - IRCCS di Reggio Emilia, Reggio Emilia, Modena, Italy.
Monica LispiInternational PhD School in Clinical and Experimental Medicine (CEM), University of Modena and Reggio Emilia, Modena, Italy.
Giovanna OrlandoMedical Affair, Merck Serono SpA, Rome, Italy.
Francesca G KlingerHistology and Embryology Section, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy.
Francesca FanelliDepartment of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy.
Adolfo Rivero-MüllerDepartment of Biochemistry and Molecular Biology, Medical University of Lublin, Lublin, Poland.
Aylin C HanyalogluInstitute of Reproductive and Developmental Biology, Imperial College London, London, UK.
Manuela SimoniUnit of Endocrinology, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Ospedale Civile Sant'Agostino-Estense, Via P. Giardini 1355, 41126 Modena, Italy.
University of Modena and Reggio Emilia · ITAzienda Unita' Sanitaria Locale Di Modena · ITAzienda Sanitaria Unità Locale di Reggio Emilia · ITCentre National de la Recherche Scientifique · FRImperial College London · GBUniversity of Rome Tor Vergata · ITInstitut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement · FRMedical University of Lublin · PLMerck (Germany) · DEMerck Serono (Italy) · ITPostgraduate School of Molecular Medicine · PLUniversity of Parma · IT
Funding
No grant is acknowledged in the PubMed record.
Abstract
Classically, follicle-stimulating hormone receptor (FSHR)-driven cAMP-mediated signaling boosts human ovarian follicle growth and oocyte maturation. However, contradicting
Indexed as
Endocrine RegulationFemale Reproductive EndocrinologyMolecular Biology
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
NCT05072353ClinicalTrials.gov
NCT07169396ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.