Evidence map›Paper›PMID 33299924›Full record

ArticleSmart health (Amsterdam, Netherlands)2020

Machine learning models for synthesizing actionable care decisions on lower extremity wounds.

Holly Nguyen, Emmanuel Agu, Bengisu Tulu, Diane Strong, Haadi Mombini, Peder Pedersen, Clifford Lindsay, Raymond Dunn, Lorraine Loretz

Open access · greenAbstract read
In one paragraph

Article in Smart health (Amsterdam, Netherlands), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. Article
  7. Multimodal AI for Home Wound Patient Referral Decisions From Images With Specialist Annotations.IEEE journal of translational engineering in health and medicine · 2025
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Holly NguyenWorcester Polytechnic Institute, 100 Institute Road, Worcester and 01609, United States.
Emmanuel AguWorcester Polytechnic Institute, 100 Institute Road, Worcester and 01609, United States.
Bengisu TuluWorcester Polytechnic Institute, 100 Institute Road, Worcester and 01609, United States.
Diane StrongWorcester Polytechnic Institute, 100 Institute Road, Worcester and 01609, United States.
Haadi MombiniWorcester Polytechnic Institute, 100 Institute Road, Worcester and 01609, United States.
Peder PedersenWorcester Polytechnic Institute, 100 Institute Road, Worcester and 01609, United States.
Clifford LindsayUniversity of Massachusetts Medical School/UMass Memorial Health Car, 55 N Lake Ave, Worcester and 01655, United States.
Raymond DunnUniversity of Massachusetts Medical School/UMass Memorial Health Car, 55 N Lake Ave, Worcester and 01655, United States.
Lorraine LoretzUniversity of Massachusetts Medical School/UMass Memorial Health Car, 55 N Lake Ave, Worcester and 01655, United States.
Worcester Polytechnic Institute · USUMass Memorial Health Care · USUniversity of Massachusetts Chan Medical School · US

Funding

SCH:Smartphone Wound Image Parameter Analysis and Decision Support in Mobile EnvR01EB025801 · NIBIB · WORCESTER POLYTECHNIC INSTITUTE · PI AGU, EMMANUEL · 2018 to 2021
$1.6M
NIBIB NIH HHS R01 EB025801
6 · The paper itself

Abstract

Lower extremity chronic wounds affect 4.5 million Americans annually. Due to inadequate access to wound experts in underserved areas, many patients receive non-uniform, non-standard wound care, resulting in increased costs and lower quality of life. We explored machine learning classifiers to generate actionable wound care decisions about four chronic wound types (diabetic foot, pressure, venous, and arterial ulcers). These decisions (target classes) were: (1) Continue current treatment, (2) Request non-urgent change in treatment from a wound specialist, (3) Refer patient to a wound specialist. We compare classification methods (single classifiers, bagged & boosted ensembles, and a deep learning network) to investigate (1) whether visual wound features are sufficient for generating a decision and (2) whether adding unstructured text from wound experts increases classifier accuracy. Using 205 wound images, the Gradient Boosted Machine (XGBoost) outperformed other methods when using both visual and textual wound features, achieving 81% accuracy. Using only visual features decreased the accuracy to 76%, achieved by a Support Vector Machine classifier. We conclude that machine learning classifiers can generate accurate wound care decisions on lower extremity chronic wounds, an important step toward objective, standardized wound care. Higher decision-making accuracy was achieved by leveraging clinical comments from wound experts.

Indexed as

Chronic woundsClassificationLower extremity ulcersMachine learning

Identifiers

PMID33299924
PMCPMC7720796
OpenAlexW3091352081

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.