Evidence map›Paper›PMID 33299747›Full record

ArticleAfrican journal of emergency medicine : Revue africaine de la medecine d'urgence2020

Clinical mortality risk factors of variceal upper gastrointestinal bleeding in a Malagasy surgical intensive care unit.

Aurélia Rakotondrainibe, Nadia M P Rahanitriniaina, Harifetra M R Randriamizao, Jasper G Raelison, Rado M Ramanampamonjy, Andriambelo T Rajaonera, François Sztark

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in African journal of emergency medicine : Revue africaine de la medecine d'urgence, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Aurélia RakotondrainibeUnité de Soins, de Formation et de Recherche, Réanimation Chirurgicale, Antananarivo - Faculté de Médecine d'Antananarivo, Université d'Antananarivo, Madagascar.
Nadia M P RahanitriniainaUnité de Soins, de Formation et de Recherche, Réanimation Chirurgicale, Antananarivo - Faculté de Médecine d'Antananarivo, Université d'Antananarivo, Madagascar.
Harifetra M R RandriamizaoUnité de Soins, de Formation et de Recherche, Réanimation Chirurgicale, Antananarivo - Faculté de Médecine d'Antananarivo, Université d'Antananarivo, Madagascar.
Jasper G RaelisonUnité de Soins, de Formation et de Recherche, Réanimation Chirurgicale, Antananarivo - Faculté de Médecine d'Antananarivo, Université d'Antananarivo, Madagascar.
Rado M RamanampamonjyUnité de Soins, de Formation et de Recherche, Hépato-gastro-entérologie, Antananarivo, Madagascar - Faculté de Médecine d'Antananarivo, Université d'Antananarivo, Madagascar.
Andriambelo T RajaoneraUnité de Soins, de Formation et de Recherche, Réanimation Chirurgicale, Antananarivo - Faculté de Médecine d'Antananarivo, Université d'Antananarivo, Madagascar.
François SztarkService d'Anesthésie-Réanimation I, CHU de Bordeaux, Place Amélie Raba Léon, Bordeaux, France - Université de Bordeaux, France.
University of Antananarivo · MGCentre Hospitalier Universitaire de Bordeaux · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVariceal upper gastrointestinal bleeding is a dreadful complication of portal hypertension with a significant morbidity and mortality. Different prognostic scores can be used. However, in the local context of Madagascar, the completion of paraclinical investigations can be delayed by the limited financial means of patients. Hence, determining clinical mortality risk factors of variceal upper gastrointestinal bleeding could be interesting. The aim of the study was to evaluate the clinical mortality risk factors of variceal gastrointestinal bleeding (VUGIB).

methodAn observational, cohort retrospective study was conducted over an 8-year period (2010-2017), at the surgical intensive care unit of the J.R. Andrianavalona University Hospital, Antananarivo, in patients admitted for VUGIB confirmed by upper gastrointestinal endoscopy and whose clinical examination was performed at admission. The primary endpoint was intensive care unit (ICU) mortality. Univariate analysis and multivariate logistic regression analysis were performed to identify risk factors for ICU mortality, with OR defining odds ratio. A

results1920 patients were admitted for gastrointestinal bleeding of any digestive causes; the source of bleeding was variceal in 269 patients (14%). The predominantly male population (sex ratio = 2.5), aged 47.1 ± 13.7 years was mostly American Society of Anesthesiologists (ASA) 1 classification (58.4%). In 56.5% of patients, the gastrointestinal bleeding had not occurred before. The mortality rate was 16.0%. Three major clinical factors of mortality were identified: previous endoscopic band variceal ligation (OR = 12.57 [2.18-72.58],

conclusionUpper gastrointestinal bleeding may be life-threatening. The mortality scores are certainly useful; however, the identification of clinical factors is interesting in countries like Madagascar, pending the results of paraclinical investigations.

Indexed as

AntananarivoClinical factorsIntensive careMortalityVariceal upper gastrointestinal bleeding

Identifiers

PMID33299747
PMCPMC7700958
OpenAlexW3044848432

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.