Evidence map›Paper›PMID 33299613›Full record

ArticleCase reports in critical care2020

Pneumothorax and Pneumomediastinum Secondary to COVID-19 Disease Unrelated to Mechanical Ventilation.

Lara Tucker, Sachin Patel, Catherine Vatsis, Antonia Poma, Ali Ammar, Wael Nasser, Satyanarayana Mukkera, Mai Vo, Rumi Khan, Steve Carlan

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in critical care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 29 citations in OpenAlex.

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  11. Pneumothorax due to COVID-19: Analysis of case reports.Respiratory medicine case reports · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Lara TuckerDepartment of Internal Medicine, Orlando Regional Healthcare, Orlando, FL, USA.
Sachin PatelDivision of Critical Care Medicine, Orlando Regional Healthcare, Orlando, FL, USA.
Catherine VatsisDepartment of Internal Medicine, Orlando Regional Healthcare, Orlando, FL, USA.
Antonia PomaDepartment of Internal Medicine, Orlando Regional Healthcare, Orlando, FL, USA.
Ali AmmarDivision of Critical Care Medicine, Orlando Regional Healthcare, Orlando, FL, USA.
Wael NasserDepartment of Faculty and Academic Affairs, University of Central Florida College of Medicine, Orlando, FL, USA.
Satyanarayana MukkeraDivision of Critical Care Medicine, Orlando Regional Healthcare, Orlando, FL, USA.
Mai VoDivision of Critical Care Medicine, Orlando Regional Healthcare, Orlando, FL, USA.
Rumi KhanDivision of Critical Care Medicine, Orlando Regional Healthcare, Orlando, FL, USA.
Steve CarlanDivision of Academic Affairs and Research, Orlando Regional Healthcare, Orlando, FL, USA.ORCID https://orcid.org/0000-0001-9867-8538
Orlando Health · USUniversity of Central Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the recent worldwide coronavirus 2019 pandemic, a notable rise in pneumomediastinum and pneumothorax complications has been witnessed in numerous mechanically ventilated patients infected with severe acute respiratory syndrome coronavirus 2. Most cases have reported these complications as barotrauma from mechanical ventilation with COVID-19 disease. We aim to report three polymerase chain reaction-confirmed COVID-19 patients who developed pneumomediastinum and pneumothorax unrelated to mechanical ventilation. We originally analyzed 800 patients with COVID-19 disease at Orlando Regional Medical Center from March 1, 2020, to July 31, 2020, of which 12 patients developed pneumomediastinum and pneumothorax in their hospital course. Interestingly, three patients developed pneumomediastinum on chest imaging prior to intubation. We present these three patients, one female and two males, ages of 42, 64, and 65, respectively, who were diagnosed with COVID-19 disease through nasopharyngeal sampling tests with acute respiratory distress syndrome. Spontaneous pneumomediastinum and pneumothorax are potential complications of COVID-19 disease in the lungs unrelated to mechanical ventilation. This is similar to previous outbreaks of severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) diseases. Further investigation is needed to define the causality of pneumomediastinum in nonintubated COVID-19 patients to define the incidence of disease.

Identifiers

PMID33299613
PMCPMC7686844
OpenAlexW3109213979

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.