Evidence map›Paper›PMID 33299610›Full record

ReviewJournal of pathogens2020

SARS-CoV-2, Early Entry Events.

James P Chambers, Jieh Yu, James J Valdes, Bernard P Arulanandam

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of pathogens, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
0.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
  2. Advancements in the Development of Anti-SARS-CoV-2 Therapeutics.International journal of molecular sciences · 2024
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Will Peptides Help to Stop COVID-19?Biochemistry. Biokhimiia · 2022
    Review
  8. The Endolysosomal System: The Acid Test for SARS-CoV-2.International journal of molecular sciences · 2022
    Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. The Role of High-Density Lipoprotein in COVID-19.Frontiers in pharmacology · 2021
    Review
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

James P ChambersSouth Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, TX, USA.ORCID https://orcid.org/0000-0001-5273-7221
Jieh YuSouth Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, TX, USA.ORCID https://orcid.org/0000-0001-8901-3366
James J ValdesSouth Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, TX, USA.
Bernard P ArulanandamSouth Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, TX, USA.ORCID https://orcid.org/0000-0002-4815-5306
Texas Center for Infectious Disease · US

Funding

Thioredoxin mediated Acinetobacter baumannii colonization in the GI tractR21AI124021 · NIAID · UNIVERSITY OF TEXAS SAN ANTONIO · PI ARULANANDAM, BERNARD PRAGASH · 2016 to 2017
$404k
NIAID NIH HHS R21 AI124021
6 · The paper itself

Abstract

Viruses are obligate intracellular parasites, and host cell entry is the first step in the viral life cycle. The SARS-CoV-2 (COVID-19) entry process into susceptible host tissue cells is complex requiring (1) attachment of the virus via the conserved spike (S) protein receptor-binding motif (RBM) to the host cell angiotensin-converting-enzyme 2 (ACE2) receptor, (2) S protein proteolytic processing, and (3) membrane fusion. Spike protein processing occurs at two cleavage sites, i.e., S

Identifiers

PMID33299610
PMCPMC7707962
OpenAlexW3110616346

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.