ArticleNeuro-oncology practice2020
An overview of the tumors affecting the spine-inside to out.
Article in Neuro-oncology practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 63 citations in OpenAlex.
- Virotherapy for Spinal and Spinal Cord Tumors: Current Evidence and Future Perspectives.Microorganisms · 2026Review
- Beyond the Spine: A Rare Case of Myxopapillary Ependymoma With Extraneural Metastases.Acta medica academica · 2026Article
- Article
- Current Trends and Future Prospects of Radiomics and Machine Learning (ML) Models in Spinal Tumors-A Narrative Review.Journal of imaging · 2026Review
- Extracellular vesicle-based therapeutic strategies for spinal tumors and associated nerve damage: advances, challenges, and future directions.Frontiers in cell and developmental biology · 2026Review
- Use of gross total resection and adjunctive therapy in treatment of spinal column tumors in low- and middle-income countries: A meta-analysis.Surgical neurology international · 2026Review
- A retrospective review of spinal masses at a South African tertiary neurosurgery unit in Durban (2020-2024).Journal of the colleges of medicine of South Africa · 2026Article
- The Breakdown of Neurovascular Barriers: Molecular Mechanisms of Tight Junction Dysfunction.Molecular neurobiology · 2025Review
- Changes in pain, quality of life, sleep, and mental health after uncomplicated spinal neurosurgery in palestine: a prospective study of patient-reported outcomes.Scientific reports · 2025Article
- Current Approach and Predictors of Clinical Outcomes in Adults With Spinal Ependymomas.Cureus · 2025Article
- Article
- En bloc resection, including the cord for tumor-free margin, in a multilevel osteosarcoma of the spine: 20-year disease-free survival. Illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Bone mineral density as potential individual prognostic biomarker in patients with neurosurgically treated spinal metastasis.Journal of cancer research and clinical oncology · 2025Article
- Use of Carbon Fiber Implants to Improve the Safety and Efficacy of Radiation Therapy for Spine Tumor Patients.Brain sciences · 2025Review
- Spinal lesions: a comprehensive radiologic overview.Frontiers in radiology · 2025Review
- An intelligent MRI data fusion framework for optimized diagnosis of spinal tumors.Frontiers in medicine · 2025Article
- Large Anterior Cervical Spine Schwannoma Causing Dysphagia: Case Report.International medical case reports journal · 2025Article
- Biportal Endoscopic Resection of Intradural Meningioma in the Cervical Spine: A Case Report.International journal of spine surgery · 2024Article
- Evolution of Thoracic Disc Herniation Surgery: Future Perspectives from a Systematic Review and Meta-Analysis.Brain sciences · 2024Review
- Bone Biopsies: Practical Considerations and Technical Tips.Seminars in interventional radiology · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Spine tumors may arise within or surrounding the spinal cord and/or vertebral column. Spinal tumors can be benign or malignant. Based on their epicenter, they may be classified as intradural-intramedullary, intradural-extramedullary, or extradural. Of these, extradural lesions are the most common, and are typically metastatic. Primary bone tumors of the spinal column comprise 5% of all primary skeletal tumors. The majority of primary spinal column tumors are benign, with malignant tumors comprising only 20%. Overall, spine metastases are the most common malignant spine tumor, and these usually arise from primaries such as lung, breast, and prostate cancers. The advent of improved systemic therapies leading to improved survival and the frequent use of imaging has positioned metastatic spine disease as the new epidemic in oncology. For spine tumors, establishing the correct diagnosis is heavily reliant on magnetic resonance imaging and histological confirmation. In this review, we will provide an overview of the epidemiology, radiological and histopathological features, and the natural history of key primary (benign and malignant) spinal cord and column tumors and metastatic spine tumors. Treatment principles for primary spinal cord or column tumors are aimed toward curative resection, whereas palliative resection forms the treatment principle for most metastatic tumors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.