Evidence map›Paper›PMID 33299540›Full record

ArticleJournal of thyroid research2020

Radial Basis Function Artificial Neural Network for the Investigation of Thyroid Cytological Lesions.

Christos Fragopoulos, Abraham Pouliakis, Christos Meristoudis, Emmanouil Mastorakis, Niki Margari, Nicolaos Chroniaris, Nektarios Koufopoulos, Alexander G Delides, Nicolaos Machairas, Vasileia Ntomi and 4 more

Abstract read
In one paragraph

Article in Journal of thyroid research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Christos FragopoulosDepartment of Cytopathology, Kavala General Hospital, Region of Eastern Macedonia and Thrace, Greece.ORCID https://orcid.org/0000-0001-9650-5748
Abraham Pouliakis2nd Department of Pathology, National and Kapodistrian University of Athens, "Attikon" University Hospital, Athens, Greece.ORCID https://orcid.org/0000-0002-0074-3619
Christos MeristoudisKlinik Diagnostik, Aalborg University Hospital, Aalborg, Denmark.ORCID https://orcid.org/0000-0002-3589-7909
Emmanouil MastorakisDepartment of Cytopathology, Venizeleion General Hospital, Heraklion, Crete, Greece.ORCID https://orcid.org/0000-0002-2982-9467
Niki Margari2nd Department of Pathology, National and Kapodistrian University of Athens, "Attikon" University Hospital, Athens, Greece.ORCID https://orcid.org/0000-0003-4975-8616
Nicolaos ChroniarisDepartment of Pathology, Venizeleion General Hospital, Heraklion, Crete, Greece.ORCID https://orcid.org/0000-0001-6457-1468
Nektarios Koufopoulos2nd Department of Pathology, National and Kapodistrian University of Athens, "Attikon" University Hospital, Athens, Greece.ORCID https://orcid.org/0000-0001-9502-7916
Alexander G Delides2nd Department of Otolaryngology-Head and Neck Surgery, National and Kapodistrian University of Athens, "Attikon" University Hospital, Athens, Greece.ORCID https://orcid.org/0000-0002-2349-2111
Nicolaos Machairas3rd Department of Surgery, National and Kapodistrian University of Athens, "Attikon" University Hospital, Athens, Greece.ORCID https://orcid.org/0000-0003-3239-3905
Vasileia Ntomi3rd Department of Surgery, National and Kapodistrian University of Athens, "Attikon" University Hospital, Athens, Greece.ORCID https://orcid.org/0000-0002-6272-1271
Konstantinos Nastos3rd Department of Surgery, National and Kapodistrian University of Athens, "Attikon" University Hospital, Athens, Greece.ORCID https://orcid.org/0000-0001-5960-6494
Ioannis G Panayiotides2nd Department of Pathology, National and Kapodistrian University of Athens, "Attikon" University Hospital, Athens, Greece.ORCID https://orcid.org/0000-0002-6394-117X
Emmanouil Pikoulis3rd Department of Surgery, National and Kapodistrian University of Athens, "Attikon" University Hospital, Athens, Greece.ORCID https://orcid.org/0000-0003-1313-1686
Evangelos P Misiakos3rd Department of Surgery, National and Kapodistrian University of Athens, "Attikon" University Hospital, Athens, Greece.ORCID https://orcid.org/0000-0002-1803-0668

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study investigates the potential of an artificial intelligence (AI) methodology, the radial basis function (RBF) artificial neural network (ANN), in the evaluation of thyroid lesions.

resultsThe RBF ANN obtained in the training set has sensitivity 82.5%, specificity 94.6%, and overall accuracy 90.3%, while in the test set, these indices were 81.4%, 90.0%, and 86.9%, respectively. Algorithm was used to classify patients on the basis of the RBF ANN, the overall sensitivity was 95.0%, the specificity was 95.5%, and no statistically significant difference was observed.

conclusionAI techniques and especially ANNs, only in the recent years, have been studied extensively. The proposed approach is promising to avoid misdiagnoses and assists the everyday practice of the cytopathology. The major drawback in this approach is the automation of a procedure to accurately detect and measure cell nuclei from the digitized images.

Identifiers

PMID33299540
PMCPMC7707952

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.