Evidence map›Paper›PMID 33299482›Full record

ArticleAnimal reproduction2020

Platelet-rich plasma (PRP) therapy: An approach in reproductive medicine based on successful animal models.

Natalia Juliana Nardelli Gonçalves, Nilo Frantz, Ricardo Manuel de Oliveira

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Animal reproduction, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05224726 (Platelet Rich Plasma for the Treatment of Uterine Scar), which is not on this map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05224726 narecruitingnot on this mapstarted 2025, after this paper: background citation

Platelet Rich Plasma for the Treatment of Uterine Scar

TypeinterventionalSponsorThe University of Texas Health Science Center, HoustonRan2025 to 2028Enrolled40ConditionsCesarean Section Complications, Uterine Bleeding, Pelvic Pain, Menstrual IrregularityArmsPlatelet Rich Plasma, Placebo
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Cell therapies for chondral defects of the talus: a systematic review.Journal of orthopaedic surgery and research · 2022
    Pooled it
  2. Platelet-rich plasma (PRP) augmentation does not result in more favourable outcomes in arthroscopic meniscal repair: a meta-analysis.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2022
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Natalia Juliana Nardelli GonçalvesRDO Medical Diagnosis, São Paulo, Brazil.
Nilo FrantzRDO Medical Diagnosis, São Paulo, Brazil.
Ricardo Manuel de OliveiraRDO Medical Diagnosis, São Paulo, Brazil.
Instituto do Sono · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Platelet-rich plasma (PRP) has been fully studied for different clinical applications in veterinary medicine for many years with promising results. As a result, therapeutic studies to elucidate pathways for PRP use in human reproduction have been performed. PRP applications in human reproductive medicine are recent, but the role of platelet growth factors in improving the endometrial environment is well known. Indications for PRP therapy show its positive effects in promoting endometrial and follicular growth and gestation in assisted reproduction cycles, as has been proven in animals. We summarized the putative role of PRP on endometrial receptivity with a brief history of promising results in research and clinical therapies.

Indexed as

infertilityPlatelet-rich plasmareproductionuterine environment

Identifiers

PMID33299482
PMCPMC7720930
OpenAlexW2921870503

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.