Evidence map›Paper›PMID 33299424›Full record

ArticleStem cells international2020

Quantification and Comprehensive Analysis of Mesenchymal Stromal Cells in Bone Marrow Samples from Sickle Cell Disease Patients with Osteonecrosis.

Tiago O Ribeiro, Paula B Daltro, Gildasio Cerqueira Daltro, Songeli M Freire, Roberto Meyer, Vitor Fortuna

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Stem cells international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Tiago O RibeiroHealth Science Institute, Federal University of Bahia, Salvador, BA 40110-100, Brazil.ORCID https://orcid.org/0000-0002-9589-7986
Paula B DaltroHealth Science Institute, Federal University of Bahia, Salvador, BA 40110-100, Brazil.ORCID https://orcid.org/0000-0003-1545-7786
Gildasio Cerqueira DaltroProf. Edgar Santos Hospital Complex, HUPES, Federal University of Bahia, Salvador, BA 40110-060, Brazil.ORCID https://orcid.org/0000-0002-4802-7953
Songeli M FreireHealth Science Institute, Federal University of Bahia, Salvador, BA 40110-100, Brazil.
Roberto MeyerHealth Science Institute, Federal University of Bahia, Salvador, BA 40110-100, Brazil.
Vitor FortunaHealth Science Institute, Federal University of Bahia, Salvador, BA 40110-100, Brazil.ORCID https://orcid.org/0000-0001-7281-3287
Universidade Federal da Bahia · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The potential use of bone marrow mesenchymal stromal cells (BM-MSCs) for the treatment of osteonecrosis in sickle cell disease (SCD) patients is increasing. However, convenient BM-MSC quantification and functional property assays are critical factors for cell-based therapies yet to be optimized. This study was designed to quantify the MSC population in bone marrow (BM) samples from SCD patients with osteonecrosis (SCD group) and patients with osteoarticular complications not related to SCD (NS group), using flow cytometry for CD271

Identifiers

PMID33299424
PMCPMC7710439
OpenAlexW3109773279

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.