Evidence map›Paper›PMID 33299395›Full record

ArticleNeural plasticity2020

Brief Mindfulness Meditation Induces Gray Matter Changes in a Brain Hub.

Rongxiang Tang, Karl J Friston, Yi-Yuan Tang

Open access · goldAbstract read
In one paragraph

Article in Neural plasticity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 53 citations in OpenAlex.

  1. Review
  2. Neuroimaging and consciousness: applications of PET, SPECT, and advanced MRI modalities.American journal of nuclear medicine and molecular imaging · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Rongxiang TangDepartment of Psychological and Brain Sciences, Washington University in St. Louis, St. Louis, MO 63105, USA.
Karl J FristonWellcome Centre for Human Neuroimaging, UCL Queen Square Institute of Neurology, University College London, London WC1N 3AR, UK.
Yi-Yuan TangDepartment of Psychological Sciences, Texas Tech University, Lubbock, TX 79409, USA.ORCID 0000-0002-6649-044X
Texas Tech University · USWashington University in St. Louis · USWellcome Centre for Human Neuroimaging · GB

Funding

Examining Mindfulness Training Effects and Mechanisms on Cognitive ControlF31AT010422 · NCCIH · WASHINGTON UNIVERSITY · PI TANG, RONGXIANG · 2019 to 2020
$78k
NCCIH NIH HHS F31 AT010422Wellcome Trust 088130/Z/09/Z
6 · The paper itself

Abstract

Previous studies suggest that the practice of long-term (months to years) mindfulness meditation induces structural plasticity in gray matter. However, it remains unknown whether short-term (<30 days) mindfulness meditation in novices could induce similar structural changes. Our previous randomized controlled trials (RCTs) identified white matter changes surrounding the anterior cingulate cortex (ACC) and the posterior cingulate cortex (PCC) within 2 to 4 weeks, following 5-10 h of mindfulness training. Furthermore, these changes were correlated with emotional states in healthy adults. The PCC is a key hub in the functional anatomy implicated in meditation and other perspectival processes. In this longitudinal study using a randomized design, we therefore examined the effect of a 10 h of mindfulness training, the Integrative Body-Mind Training (IBMT) on gray matter volume of the PCC compared to an active control-relaxation training (RT). We found that brief IBMT increased ventral PCC volume and that baseline temperamental trait-an index of individual differences was associated with a reduction in training-induced gray matter increases. Our findings indicate that brief mindfulness meditation induces gray matter plasticity, suggesting that structural changes in ventral PCC-a key hub associated with self-awareness, emotion, cognition, and aging-may have important implications for protecting against mood-related disorders and aging-related cognitive declines.

Indexed as

MindfulnessAdultCerebral CortexEmotionsFemaleGray MatterGyrus CinguliHumansIndividualityMaleMeditationRelaxation TherapyYoung Adult

Identifiers

PMID33299395
PMCPMC7704181
OpenAlexW3102472735

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.