Evidence map›Paper›PMID 33299345›Full record

ArticleJournal of pain research2020

Anatomical Study of the Innervation of the Masseter Muscle and Its Correlation with Myofascial Trigger Points.

Roberto Procópio Pinheiro, Matheus Aquesta Gaubeur, Ana Maria Itezerote, Samir Omar Saleh, Flávio Hojaij, Mauro Andrade, Alfredo Luiz Jacomo, Flávia Emi Akamatsu

Open access · goldAbstract read
In one paragraph

Article in Journal of pain research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

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  9. Nociplastic pain: controversy of the concept.The Korean journal of pain · 2025
    Review
  10. Anatomical Bases of the Temporal Muscle Trigger Points.BioMed research international · 2024
    Article
  11. Trigeminal somatosensation in the temporomandibular joint and associated disorders.Frontiers in pain research (Lausanne, Switzerland) · 2024
    Review
  12. Review
  13. Review
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Roberto Procópio PinheiroDepartment of Surgery, Laboratory of Medical Research-Division of Human Structural Topography, Faculty of Medicine of the University of São Paulo (FMUSP), São Paulo, SP, 01246903, Brazil.
Matheus Aquesta GaubeurDepartment of Surgery, Laboratory of Medical Research-Division of Human Structural Topography, Faculty of Medicine of the University of São Paulo (FMUSP), São Paulo, SP, 01246903, Brazil.ORCID 0000-0002-2623-7749
Ana Maria ItezeroteDepartment of Surgery, Laboratory of Medical Research-Division of Human Structural Topography, Faculty of Medicine of the University of São Paulo (FMUSP), São Paulo, SP, 01246903, Brazil.
Samir Omar SalehDepartment of Surgery, Laboratory of Medical Research-Division of Human Structural Topography, Faculty of Medicine of the University of São Paulo (FMUSP), São Paulo, SP, 01246903, Brazil.ORCID 0000-0002-3934-3110
Flávio HojaijDepartment of Surgery, Laboratory of Medical Research-Division of Human Structural Topography, Faculty of Medicine of the University of São Paulo (FMUSP), São Paulo, SP, 01246903, Brazil.ORCID 0000-0003-0080-022X
Mauro AndradeDepartment of Surgery, Laboratory of Medical Research-Division of Human Structural Topography, Faculty of Medicine of the University of São Paulo (FMUSP), São Paulo, SP, 01246903, Brazil.ORCID 0000-0002-1887-8669
Alfredo Luiz JacomoDepartment of Surgery, Laboratory of Medical Research-Division of Human Structural Topography, Faculty of Medicine of the University of São Paulo (FMUSP), São Paulo, SP, 01246903, Brazil.ORCID 0000-0001-9546-3873
Flávia Emi AkamatsuDepartment of Surgery, Laboratory of Medical Research-Division of Human Structural Topography, Faculty of Medicine of the University of São Paulo (FMUSP), São Paulo, SP, 01246903, Brazil.ORCID 0000-0003-1088-0075
Universidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeMyofascial pain syndrome (MPS) is widely prevalent in the general population; some reports estimate its prevalence ranges from 9 to 85%. Among the different locations where MPS may arise, pain related to the masseter muscle is referred as masticatory myofascial pain. MPS is characterized by myofascial trigger points (MTPs), which represent tender anatomical areas of a muscle where painful symptoms are elicited whenever stimulated. Previous publications have found MTPs to coincide with neuromuscular junctions at the motor end plate, at the innervation zone (IZ). Our study aimed to describe the innervation of the masseter muscle and relate it to clinically described myofascial trigger points (MTPs). MATERIALS AND

methodsWe mapped the nerve fiber distribution into the masseter muscles from 16 cadavers by anatomical dissection. We divided the muscle into six regions, three superior (I-III) and three inferior (IV-VI), and classified the nerve's branches distribution according to these predetermined areas. Statistical analyses was made by Poisson distribution and logarithm link function followed by Bonferroni multiple comparisons (

resultsAll six areas received branches from the masseteric nerve. Areas I and II (upper posterior and upper intermediate, respectively) had a significant higher number of nerve entries as compared to the remaining areas.

conclusionThe penetration areas of the masseteric nerve have been established and MTPs are found in the innervation zones, clinicians should focus initially on the regions of the penetration points, for diagnostics and therapeutic measures, such as injections, dry needling and soft tissue interventions. Anatomical study of nerve supply to the masseter muscle can provide useful additional knowledge to further understanding masticatory myofascial pain and to direct therapeutic interventions and diagnostic studies of temporomandibular junction dysfunction.

Indexed as

anatomyinnervation zonemasseteric nervepain

Identifiers

PMID33299345
PMCPMC7719441
OpenAlexW3110087383

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.