ArticleInternational journal of general medicine2020
The Prevalence of Isolated Neutropenia at High Altitude in Southern Saudi Arabia: Does Altitude Affect Leucocyte Count?
Article in International journal of general medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Hematological parameters' reference intervals in apparently healthy individuals in Saudi Arabia: a systematic review and meta-analysis.Frontiers in medicine · 2025Pooled it
- Derivation of Russian-specific reference intervals for complete blood count, iron markers and related vitamins.PloS one · 2024Article
- Clinical characteristics and predictors of pulmonary hypertension in chronic obstructive pulmonary disease at different altitudes.BMC pulmonary medicine · 2023Article
- Adaptation and altitude sickness: A 40-year bibliometric analysis and collaborative networks.Frontiers in public health · 2023Article
- Prevalence of neutropenia among adult Arabs in Qatar: Relation to other hematological parameters and anthropometric data.Medicine · 2022Article
- A Critical Analysis of the Automated Hematology Assessment in Pregnant Women at Low and at High Altitude: Association between Red Blood Cells, Platelet Parameters, and Iron Status.Life (Basel, Switzerland) · 2022Article
- Monocytohigh-density lipoprotein ratio has a high predictive value for the diagnosis of multiple system atrophy and the differentiation from Parkinson's disease.Frontiers in aging neuroscience · 2022Article
- Hematological indices in the adult saudi population: Reference intervals by gender, age, and region.Frontiers in medicine · 2022Article
- Isolated Neutropenia/Benign Ethnic Neutropenia: A Common Clinical and Laboratory Finding in Southern and Western Saudi Arabia.International journal of general medicine · 2021Article
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionIsolated neutropenia is a common problem in hematology practice. Benign ethnic neutropenia (BEN) is the common form of neutropenia worldwide and it affects mainly African and Middle Eastern ethnicities. Most cases of isolated mild and moderate neutropenia are benign and associated with no clinical significance. The aim of this study was to estimate the prevalence of isolated neutropenia at high-altitude southern Saudi Arabia.
methodsA large dataset of complete blood counts (CBCs) was analyzed for walk-in patients of both genders, of age ranges from 12 to 60 years doing blood tests at a commercial lab for high altitude - 2,270 meters above sea level - (HA) group, and from sea level SL group. Abnormal biochemical or CBC results were excluded before analysis.
resultsFor HA group, 3123 CBCs were analyzed and for SL group 18,427 CBCs were analyzed. The prevalence of mild neutropenia, defined as absolute neutrophil count (ANC) in the range of 1.0-.5× 10
conclusionIsolated neutropenia is common in Saudis living at high altitude. While benign ethnic neutropenia (BEN) is thought to be the major contributing factor to this high prevalence, other factors including environmental factors and altitude are possible contributing factors along with underlying ethnic neutropenia.
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