Evidence map›Paper›PMID 33299301›Full record

ArticleDrug design, development and therapy2020

Evaluation of the Effect of

Karem H Alzoubi, Laila Abdel-Hafiz, Omar F Khabour, Tamam El-Elimat, Mohammad A Alzubi, Feras Q Alali

Open access · goldAbstract read
In one paragraph

Article in Drug design, development and therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
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  12. Folecitin Isolated fromEvidence-based complementary and alternative medicine : eCAM · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 4 countries.

Karem H Alzoubi *Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid 22110, Jordan.ORCID 0000-0002-2808-5099
Laila Abdel-Hafiz *Institute of Anatomy II, Medical Faculty, Heinrich Heine Universität, Düsseldorf, Germany.
Omar F KhabourDepartment of Medical Laboratory Sciences, Jordan University of Science and Technology, Irbid 22110, Jordan.ORCID 0000-0002-3006-3104
Tamam El-ElimatDepartment of Medicinal Chemistry and Pharmacognosy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid 22110, Jordan.ORCID 0000-0002-9246-4974
Mohammad A AlzubiIntegrative Life Sciences Doctoral Program, Department of Pathology, Virginia Commonwealth University, Richmond, VA, USA.
Feras Q AlaliCollege of Pharmacy, QU Health, Qatar University, Doha Qatar.
Jordan University of Science and Technology · JOQatar University · QAVirginia Commonwealth University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic psychosocial stress impairs memory function and leads to a depression-like phenotype induced by a persistent status of oxidative stress.

objectiveTo determine whether chronic treatment with

methodsThe radial arm water maze (RAWM) was used to test learning and memory in rats exposed to daily stress using the resident-intruder paradigm. Stressed and unstressed rats received chronic

resultsNeither chronic stress nor chronic

conclusion

Indexed as

AnimalsAntidepressive AgentsBrain-Derived Neurotrophic FactorHippocampusHypericumMaleMemory DisordersPlant ExtractsRatsRats, WistarStress, PsychologicalAntidepressive AgentsBdnf protein, ratBrain-Derived Neurotrophic FactorPlant ExtractsBDNFhippocampusHypericum triquetrifoliumlearningmemorymethanolic extractstress

Identifiers

PMID33299301
PMCPMC7720289
OpenAlexW3108757333

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.