Evidence map›Paper›PMID 33299258›Full record

ArticleTetrahedron letters2020

Superacid-promoted synthesis of quinoline derivatives.

Hein Vuong, Michael R Stentzel, Douglas A Klumpp

Abstract read
In one paragraph

Article in Tetrahedron letters, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hein VuongDepartment of Chemistry and Biochemistry, Northern Illinois University, DeKalb, IL 60115.
Michael R StentzelDepartment of Chemistry and Biochemistry, Northern Illinois University, DeKalb, IL 60115.
Douglas A KlumppDepartment of Chemistry and Biochemistry, Northern Illinois University, DeKalb, IL 60115.

Funding

Conjugate Addition in the Synthesis of Biologically Active N-HererocyclesR15GM126498 · NIGMS · NORTHERN ILLINOIS UNIVERSITY · PI KLUMPP, DOUGLAS A · 2018 to 2018
$421k
NIGMS NIH HHS R15 GM126498
6 · The paper itself

Abstract

A series of vinylogous imines have been prepared from anilines and cinnamaldehydes. These substrates react in superacidic media to provide quinolines and related compounds. A mechanism for the conversion is proposed which involves the cyclization of dicationic superelectrophilic intermediates. Aromatization of the quinoline ring is thought to occur by superacid-promoted elimination of benzene.

Indexed as

CyclizationHeterocycleQuinolineSuperacidSuperelectrophile

Identifiers

PMID33299258
PMCPMC7720793

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.