ArticleNature2020
Lymphoangiocrine signals promote cardiac growth and repair.
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Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 125 papers.
0numbers the graph read from it
0cells of the map it votes in
125citing papers in PubMed
8.3field-weighted citation impact, top 2% of its field
What it found
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Who cites it
125 citing papers in PubMed, 195 citations in OpenAlex.
- Cardiac lymphatic dysfunction and repair in cardiovascular disease.Nature reviews. Cardiology · 2026Review
- Age-associated loss of lymphatic vessels promotes cardiac inflammation.Nature cardiovascular research · 2026Article
- Bone Lymphatic Endothelial Cells Form a Distinct Skeletal Population and Drive Skeletal Repair.bioRxiv : the preprint server for biology · 2026Article
- Cardiac immunity and heart repair: Mechanism, challenge, and future direction.Chinese medical journal · 2026Review
- Neurovascular interactions in the ageing heart.Nature reviews. Cardiology · 2026Review
- Blood and lymphatic vascular network in bone injury repair: from molecular mechanisms to therapeutic strategies.Science China. Life sciences · 2026Review
- Inhibiting L-type calcium channel promotes cardiomyocyte proliferation through activating the canonical Wnt signaling pathway.Acta pharmacologica Sinica · 2026Article
- Rejuvenating the damaged and aged heart: lessons from development.npj biomedical innovations · 2026Review
- LYVE1 ectodomain shedding blunts lymphatic transmigration and clearance of macrophages during kidney injury.JCI insight · 2026Article
- Cell-free strategies for cardiomyocyte proliferation and heart repair.Pharmacological reports : PR · 2026Review
- Possible Impact of Lymphatic Drainage on Brain Injury After Aneurysmal Subarachnoid Hemorrhage.International journal of molecular sciences · 2026Review
- Molecular determinants of cardiac lymphatic dysfunction in a chronic pressure-overload model.EMBO molecular medicine · 2026Article
- The role of the cardiac lymphatic system in heart failure "reverse remodeling": from developmental signals to druggable targets.Frontiers in immunology · 2026Review
- Lymphatic-stem cell crosstalk promotes tendon regeneration via Notch1-Srebp2-mediated cholesterol metabolism.Nature communications · 2025Article
- Molecular Mechanisms and Therapeutic Strategies Targeting Cardiac Lymphangiogenesis in Heart Failure.Cardiovascular toxicology · 2025Review
- Regional and cell specific bioactivity of injectable extracellular matrix biomaterials in myocardial infarction.Nature communications · 2025Article
- An infusible decellularized extracellular matrix material binds to vasculature in infarcted myocardium and induces pro-reparative gene expression following acute myocardial infarction through inherent avidity and bioactive signaling.bioRxiv : the preprint server for biology · 2025Article
- Molecular gatekeepers of endogenous adult mammalian cardiomyocyte proliferation.Nature reviews. Cardiology · 2025Review
- Maintaining the LYVE1 line through macrophage and lymphatic interplay in the regenerating neonatal heart.Nature cardiovascular research · 2025Article
- Cardiac lymphatics retain LYVE-1-dependent macrophages during neonatal mouse heart regeneration.Nature cardiovascular research · 2025Article
65 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
17 authors at 4 institutions in 3 countries.
Xiaolei LiuCenter for Vascular and Developmental Biology, Feinberg Cardiovascular and Renal Research Institute, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Ester De la CruzCardiovascular Development Program, Centro Nacional de Investigaciones Cardiovasculares, CNIC, Madrid, Spain.
Xiaowu GuDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID http://orcid.org/0000-0003-2266-5516
Laszlo BalintDepartment of Physiology, Semmelweis University School of Medicine, Budapest, Hungary.ORCID http://orcid.org/0000-0002-3142-4071
Michael Oxendine-BurnsCenter for Vascular and Developmental Biology, Feinberg Cardiovascular and Renal Research Institute, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.ORCID http://orcid.org/0000-0002-8054-0757
Tamara TerronesDepartment of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Wanshu MaCenter for Vascular and Developmental Biology, Feinberg Cardiovascular and Renal Research Institute, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Hui-Hsuan KuoDepartment of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.ORCID http://orcid.org/0000-0001-8266-7105
Connor LantzDepartment of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.ORCID http://orcid.org/0000-0003-3317-6486
Trisha BansalCenter for Vascular and Developmental Biology, Feinberg Cardiovascular and Renal Research Institute, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Edward ThorpDepartment of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.ORCID http://orcid.org/0000-0003-1387-7058
Paul BurridgeDepartment of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.ORCID http://orcid.org/0000-0001-9616-0006
Zoltán JakusDepartment of Physiology, Semmelweis University School of Medicine, Budapest, Hungary.ORCID http://orcid.org/0000-0002-6304-2369
Joachim HerzDepartment of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Ondine CleaverDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Miguel TorresCardiovascular Development Program, Centro Nacional de Investigaciones Cardiovasculares, CNIC, Madrid, Spain.ORCID http://orcid.org/0000-0003-0906-4767
Guillermo OliverCenter for Vascular and Developmental Biology, Feinberg Cardiovascular and Renal Research Institute, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. guillermo.oliver@northwestern.edu.ORCID http://orcid.org/0000-0003-3984-7615
Northwestern University · USThe University of Texas Southwestern Medical Center · USSemmelweis University · HUSpanish National Centre for Cardiovascular Research · ES
Funding
Tumor Environment and Metastasis (TEAM) Research ProgramP30CA060553 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Daniela E Matei · 1993 to 2026
$153.9MCELLULAR &MOLECULAR BASIS OF DISEASE TRAINING PROGRAMT32GM008061 · NIGMS · NORTHWESTERN UNIVERSITY · PI CARTHEW, RICHARD W. · 1985 to 2022
$17.1MTR&D 7: Cell Specific ProteomicsP41GM108569 · NIGMS · NORTHWESTERN UNIVERSITY · PI KELLEHER, NEIL L · 2015 to 2024
$13.6MPrecision Cell Isolation and Analysis CoreP01AI112522 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ABECASSIS, MICHAEL M · 2015 to 2019
$11.9MProx1 in Mammalian LymphangiogenesisR01HL073402 · NHLBI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI OLIVER, GUILLERMO C · 2003 to 2020
$7.3MTherapeutics Development Core (Core B)P30DK114857 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SCHNAPER, H WILLIAM · 2018 to 2022
$5.7MEfferocytosis-Directed Inflammation Resolution and Repair in the Hypoxic HeartR01HL122309 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI THORP, EDWARD BENJAMIN · 2014 to 2024
$5.0MMetabolism of the VLDL receptor and ApoE receptor 2R37HL063762 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI HERZ, JOACHIM J · 2010 to 2019
$4.0MMETABOLISM OF THE VLDL RECEPTOR AND APOE RECEPTOR 2R01HL063762 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI HERZ, JOACHIM J · 2000 to 2009
$3.1MFunctional roles of lymphatics in organogenesis and tissue repairR01HL151388 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI OLIVER, GUILLERMO C · 2021 to 2024
$2.5MMolecular Basis of Synaptic Suppression by ApoER01NS093382 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI HERZ, JOACHIM J · 2016 to 2020
$2.0MNorthwestern University Molecular and Translational Cardiovascular Training ProgramT32HL134633 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MCNALLY, ELIZABETH M · 2017 to 2021
$1.6MNCI NIH HHS P30 CA060553NCRR NIH HHS S10 RR031680NHLBI NIH HHS R01 HL063762NHLBI NIH HHS R01 HL073402NHLBI NIH HHS R01 HL122309NHLBI NIH HHS R01 HL151388NHLBI NIH HHS R37 HL063762NHLBI NIH HHS T32 HL134633NIAID NIH HHS P01 AI112522NIDDK NIH HHS P30 DK114857NIGMS NIH HHS P41 GM108569NIGMS NIH HHS T32 GM008061NIH HHS S10 OD011996NIH HHS S10 OD025194NIH HHS S10 OD026814NINDS NIH HHS R01 NS093382
Abstract
Recent studies have suggested that lymphatics help to restore heart function after cardiac injury
Indexed as
RegenerationSignal TransductionAnimalsAnimals, NewbornApoptosisCell Adhesion Molecules, NeuronalCell ProliferationCells, CulturedCell SurvivalEndothelial CellsExtracellular Matrix ProteinsFemaleHeartHumansIntegrin beta1Lymphatic SystemCell Adhesion Molecules, NeuronalExtracellular Matrix ProteinsIntegrin beta1Nerve Tissue ProteinsReelin ProteinRELN protein, humanReln protein, mouseSerine Endopeptidases
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.