Evidence map›Paper›PMID 33299184›Full record

ArticleNature2020

The functional proteome landscape of Escherichia coli.

André Mateus, Johannes Hevler, Jacob Bobonis, Nils Kurzawa, Malay Shah, Karin Mitosch, Camille V Goemans, Dominic Helm, Frank Stein, Athanasios Typas and 1 more

Abstract read
In one paragraph

Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed.

  1. Article
  2. Article
  3. Bacterial stress responses lower mRNA-protein level correlations.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Dual regulation ofmicroLife · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

André MateusGenome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.ORCID http://orcid.org/0000-0001-6870-0677
Johannes HevlerGenome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.ORCID http://orcid.org/0000-0001-6636-7145
Jacob BobonisGenome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.ORCID http://orcid.org/0000-0001-9293-9733
Nils KurzawaGenome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.ORCID http://orcid.org/0000-0002-7846-2817
Malay ShahGenome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.
Karin MitoschGenome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.
Camille V GoemansGenome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.ORCID http://orcid.org/0000-0002-5564-1644
Dominic HelmProteomics Core Facility, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.ORCID http://orcid.org/0000-0001-9321-2069
Frank SteinProteomics Core Facility, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.ORCID http://orcid.org/0000-0001-9695-1692
Athanasios TypasGenome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany. typas@embl.de.ORCID http://orcid.org/0000-0002-0797-9018
Mikhail M SavitskiGenome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany. mikhail.savitski@embl.de.ORCID http://orcid.org/0000-0003-2011-9247

Funding

European Research Council 819454
6 · The paper itself

Abstract

Recent developments in high-throughput reverse genetics

Indexed as

Protein StabilityTemperatureEnzyme ActivationEscherichia coliEscherichia coli ProteinsGene Expression Regulation, BacterialMutant ProteinsMutationPhenotypeProteomeProteomicsReverse GeneticsEscherichia coli ProteinsMutant ProteinsProteome

Identifiers

PMID33299184
PMCPMC7612278

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.