ArticleNature2021
Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture.
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Article in Nature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 165 papers.
0numbers the graph read from it
0cells of the map it votes in
165citing papers in PubMed
14.1field-weighted citation impact, top 1% of its field
What it found
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Who cites it
165 citing papers in PubMed, 262 citations in OpenAlex.
- Origins and consequences of oncogenic 3D chromatin remodelling.Nature reviews. Cancer · 2026Review
- Molecular predictors of minimal residual disease in newly diagnosed multiple myeloma treated with quadruplet therapy.Nature medicine · 2026Article
- FetchPA: a guided, end-to-end solution for local ATAC-Seq data processing and analyses.bioRxiv : the preprint server for biology · 2026Article
- Impact of Trastuzumab and Pertuzumab on HER2 Localization and the Estrogen Receptor Cistrome in ER+/HER2+ Breast Cancer.bioRxiv : the preprint server for biology · 2026Article
- The roles of chromatin remodeling and 3D genome organization in cancers: from mechanistic insights to emerging treatment options.Molecular cancer · 2026Review
- Malignant B-cell States Orchestrate Spatially Organized Immune Ecosystems in B-cell Lymphomas.Research square · 2026Article
- Article
- 3D chromatin structure remodelling in cancer.Cell communication and signaling : CCS · 2026Review
- Host heterogeneity shapes clonal selection and organotropism in an extranodal lymphoma mouse model.Cell death & disease · 2026Article
- Review
- H3K27me3 spreading organizes canonical PRC1 chromatin architecture to regulate developmental programs.Nature genetics · 2026Article
- The conserved N-terminal SANT1-binding domain (SBD) of EZH2 regulates PRC2 activity.Genes & development · 2026Article
- Linker histone H1 functions as a liquid-like glue to organize chromatin in living human cells.Science advances · 2026Article
- Linker histones consolidate heterogenous nucleosome fiber contacts by linking together multiple nucleosomes.Nature communications · 2026Article
- Clinical application of PARP inhibitors and emerging strategies to overcome resistance: a pan-cancer perspective.Biomarker research · 2026Review
- Nucleosome spacing across cell types, diseases, and ages.Nucleic acids research · 2026Review
- T follicular helper cells transiently unlock a plasticity state in germinal centre B cells during the humoral immune response.Nature cell biology · 2026Article
- Discovering the abnormalities and functional importance of ferroptosis-related molecules in cervical cancer.International journal of medical sciences · 2026Article
- SLC41A2 Suppresses Colon Cancer Progression by Inhibiting GSK3β Ubiquitin-proteasome Degradation.Current molecular medicine · 2026Article
- Article
105 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
29 authors at 12 institutions in 4 countries.
Nevin YusufovaDivision of Hematology and Medical Oncology, Sanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, NY, USA.
Andreas KloetgenDepartment of Pathology, NYU School of Medicine, New York, NY, USA.ORCID http://orcid.org/0000-0003-0991-4442
Matt TeaterDivision of Hematology and Medical Oncology, Sanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, NY, USA.
Adewola OsunsadeChemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID http://orcid.org/0000-0001-6340-8765
Jeannie M CamarilloDepartment of Chemistry, Northwestern University, Evanston, IL, USA.ORCID http://orcid.org/0000-0001-9699-0931
Christopher R ChinDepartment of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA.ORCID http://orcid.org/0000-0002-2140-3197
Ashley S DoaneTri-Institutional PhD Program in Computational Biomedicine, New York, NY, USA.ORCID http://orcid.org/0000-0002-1489-1786
Bryan J VentersEpiCypher, Durham, NC, USA.
Stephanie Portillo-LedesmaDepartment of Chemistry, New York University, New York, NY, USA.
Joseph ConwayDepartment of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.
Jude M PhillipDivision of Hematology and Medical Oncology, Sanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, NY, USA.
Olivier ElementoDepartment of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA.
David W ScottCentre for Lymphoid Cancer, BC Cancer, Vancouver, British Columbia, Canada.
Wendy BéguelinDivision of Hematology and Medical Oncology, Sanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, NY, USA.
Jonathan D LichtUniversity of Florida Health Cancer Center, The University of Florida Cancer and Genetics Research Complex, Gainesville, FL, USA.ORCID http://orcid.org/0000-0002-3942-1369
Neil L KelleherDepartment of Chemistry, Northwestern University, Evanston, IL, USA.ORCID http://orcid.org/0000-0002-8815-3372
Louis M StaudtLymphoid Malignancies Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Arthur I SkoultchiDepartment of Cell Biology, Albert Einstein College of Medicine, New York, NY, USA.ORCID http://orcid.org/0000-0001-5096-8077
Michael-Christopher KeoghEpiCypher, Durham, NC, USA.ORCID http://orcid.org/0000-0002-2219-8623
Effie ApostolouSanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, NY, USA.ORCID http://orcid.org/0000-0002-8111-0863
Christopher E MasonDepartment of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA.ORCID http://orcid.org/0000-0002-1850-1642
Marcin ImielinskiDepartment of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.ORCID http://orcid.org/0000-0002-2211-4741
Tamar SchlickDepartment of Chemistry, New York University, New York, NY, USA.
Yael DavidChemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID http://orcid.org/0000-0003-1696-0025
Aristotelis TsirigosDepartment of Pathology, NYU School of Medicine, New York, NY, USA.ORCID http://orcid.org/0000-0002-7512-8477
C David AllisLaboratory of Chromatin Biology and Epigenetics, The Rockefeller University, New York, NY, USA.
Alexey A SoshnevLaboratory of Chromatin Biology and Epigenetics, The Rockefeller University, New York, NY, USA. asoshnev@rockefeller.edu.ORCID http://orcid.org/0000-0002-1713-3470
Ethel CesarmanDepartment of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA. ecesarm@med.cornell.edu.ORCID http://orcid.org/0000-0003-3303-6299
Ari M MelnickDivision of Hematology and Medical Oncology, Sanford I. Weill Department of Medicine, Weill Cornell Medicine, New York, NY, USA. amm2014@med.cornell.edu.ORCID http://orcid.org/0000-0002-8074-2287
Cornell University · USEpiCypher (United States) · USMemorial Sloan Kettering Cancer Center · USNew York University · USNorthwestern University · USRockefeller University · USAlbert Einstein College of Medicine · USHelmholtz Centre for Infection Research · DENational Institutes of Health · USNew York University Shanghai · CNSpinal Cord Injury BC · CAUniversity of Florida Health · US
Funding
X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Elisa de Stanchina · 1985 to 2026
$347.4MTumor Environment and Metastasis (TEAM) Research ProgramP30CA060553 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Daniela E Matei · 1993 to 2026
$153.9MOncogenic mechanisms and molecular targets in lymphomaZIABC011008 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI STAUDT, LOUIS · 2009 to 2025
$21.0MShared Resources Core 2: Quantitative Proteomics CoreP01CA196539 · NCI · ROCKEFELLER UNIVERSITY · PI MAJEWSKI, JACEK · 2015 to 2024
$17.6MThe impact of changes in chromatin architecture on cancer phenotypes and tumor progressionP01CA229086 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ADRIANA HEGUY · 2019 to 2026
$17.0MTR&D 7: Cell Specific ProteomicsP41GM108569 · NIGMS · NORTHWESTERN UNIVERSITY · PI KELLEHER, NEIL L · 2015 to 2024
$13.6MSpatio-Temporal Organization of Chromatin and Information Transfer in CancerU54CA193419 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI O'HALLORAN, THOMAS V · 2015 to 2020
$10.4MTargeting Epigenetic Circuits in B-Cell LymphomasR35CA220499 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI MELNICK, ARI M. · 2018 to 2024
$7.2MBridging Disparate Structural/Functional Scales: Multiscale Modeling of the Chromatin Fiber and RNA Tertiary StructuresR35GM122562 · NIGMS · NEW YORK UNIVERSITY · PI Tamar Schlick · 2017 to 2026
$4.6MTargeting Epigenetic Heterogeneity in Pediatric T cell leukemia: Epi-Clones as Drivers of ChemoresistanceR01CA252239 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Aristotelis Tsirigos · 2021 to 2026
$3.7MRole of novel onco-histone mutations in B-cell malignanciesR01CA234561 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI CESARMAN, ETHEL · 2019 to 2023
$3.3MThe identification and validation of mechanisms and biomarkers for relapse in diffuse large B-cell lymphoma (Administrative Supplement)R01CA194547 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI ELEMENTO, OLIVIER, TAM, WAYNE · 2015 to 2019
$2.6MNCI NIH HHS P01 CA196539NCI NIH HHS P01 CA229086NCI NIH HHS P30 CA008748NCI NIH HHS P30 CA060553NCI NIH HHS R01 CA194547NCI NIH HHS R01 CA195732NCI NIH HHS R01 CA228528NCI NIH HHS R01 CA234561NCI NIH HHS R01 CA252239NCI NIH HHS R35 CA220499NCI NIH HHS U54 CA193419NIDCR NIH HHS R44 DE029633NIGMS NIH HHS P41 GM108569NIGMS NIH HHS R01 GM116143NIGMS NIH HHS R01 GM147165NIGMS NIH HHS R35 GM122562NIGMS NIH HHS R35 GM138386NIGMS NIH HHS R44 GM116584NIH HHS S10 OD025194
Abstract
Linker histone H1 proteins bind to nucleosomes and facilitate chromatin compaction
Indexed as
AllelesAnimalsB-LymphocytesCell Self RenewalCell Transformation, NeoplasticChromatinChromatin Assembly and DisassemblyEpigenesis, GeneticGene Expression Regulation, NeoplasticGene SilencingGenes, Tumor SuppressorGerminal CenterHistonesHumansLymphomaMiceChromatinHistones
Identifiers
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.