Evidence map›Paper›PMID 33299180›Full record

ArticleNature2021

Bidirectional perisomatic inhibitory plasticity of a Fos neuronal network.

Ee-Lynn Yap, Noah L Pettit, Christopher P Davis, M Aurel Nagy, David A Harmin, Emily Golden, Onur Dagliyan, Cindy Lin, Stephanie Rudolph, Nikhil Sharma and 3 more

Open access · greenAbstract read
In one paragraph

Article in Nature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed, 2 pooled it
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 2 syntheses or guidelines pooled it, 158 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. The role of GABANeuroscience and biobehavioral reviews · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. NPAS4 refines spatial and temporal firing in CA1 pyramidal neurons.bioRxiv : the preprint server for biology · 2026
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Ee-Lynn YapDepartment of Neurobiology, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0001-6537-508X
Noah L PettitDepartment of Neurobiology, Harvard Medical School, Boston, MA, USA.
Christopher P DavisDepartment of Neurobiology, Harvard Medical School, Boston, MA, USA.
M Aurel NagyDepartment of Neurobiology, Harvard Medical School, Boston, MA, USA.
David A HarminDepartment of Neurobiology, Harvard Medical School, Boston, MA, USA.
Emily GoldenDepartment of Neurobiology, Harvard Medical School, Boston, MA, USA.
Onur DagliyanDepartment of Neurobiology, Harvard Medical School, Boston, MA, USA.
Cindy LinDepartment of Neurobiology, Harvard Medical School, Boston, MA, USA.
Stephanie RudolphDepartment of Neurobiology, Harvard Medical School, Boston, MA, USA.
Nikhil SharmaDepartment of Neurobiology, Harvard Medical School, Boston, MA, USA.
Eric C GriffithDepartment of Neurobiology, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0003-0428-3215
Christopher D HarveyDepartment of Neurobiology, Harvard Medical School, Boston, MA, USA.
Michael E GreenbergDepartment of Neurobiology, Harvard Medical School, Boston, MA, USA. michael_greenberg@hms.harvard.edu.ORCID http://orcid.org/0000-0003-1380-2160
Harvard University · US

Funding

Medical Scientist Training ProgramT32GM007753 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI WALENSKY, LOREN DAVID · 1985 to 2021
$50.0M
ELECTRICAL STIMULATION OF IMMEDIATE EARLY GENESR37NS028829 · NINDS · HARVARD MEDICAL SCHOOL · PI GREENBERG, MICHAEL ELDON · 1999 to 2019
$7.4M
Supplement request for Training GrantT32NS007473 · NINDS · CHILDREN'S HOSPITAL BOSTON · PI Elizabeth C. Engle, Thomas L. Schwarz · 1999 to 2026
$6.9M
ELECTRICAL STIMULATION OF IMMEDIATE GENESR01NS028829 · NINDS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI GREENBERG, MICHAEL ELDON · 1990 to 2024
$6.2M
Toward mechanistic cognitive neuroscience: cell types, connectivity, and patterned perturbationsDP1MH125776 · NIMH · HARVARD MEDICAL SCHOOL · PI HARVEY, CHRISTOPHER D · 2020 to 2024
$5.9M
Super-Resolution ImagingP30NS072030 · NINDS · HARVARD MEDICAL SCHOOL · PI REGEHR, WADE G · 2011 to 2020
$5.8M
Parietal Cortex Networks for Sensorimotor Processing During NavigationR01NS089521 · NINDS · HARVARD MEDICAL SCHOOL · PI HARVEY, CHRISTOPHER D · 2015 to 2024
$4.5M
Mechanisms Underlying Neuronal Enhancer Specification During Postnatal CNS DevelopmentR01NS115965 · NINDS · HARVARD MEDICAL SCHOOL · PI GREENBERG, MICHAEL ELDON · 2020 to 2024
$3.2M
Specification of Neuronal Enhancers during Postnatal DevelopmentF32NS112455 · NINDS · HARVARD MEDICAL SCHOOL · PI DAVIS, CHRISTOPHER PATRICK · 2019 to 2021
$149k
NIGMS NIH HHS T32 GM007753NIMH NIH HHS DP1 MH125776NINDS NIH HHS F32 NS112455NINDS NIH HHS P30 NS072030NINDS NIH HHS R01 NS028829NINDS NIH HHS R01 NS089521NINDS NIH HHS R01 NS115965NINDS NIH HHS R37 NS028829NINDS NIH HHS T32 NS007473
6 · The paper itself

Abstract

Behavioural experiences activate the FOS transcription factor in sparse populations of neurons that are critical for encoding and recalling specific events

Indexed as

Neural InhibitionAnimalsCA1 Region, HippocampalCholecystokininExploratory BehaviorFemaleGamma RhythmInterneuronsMaleMemory ConsolidationMiceNerve NetNeuronal PlasticityParvalbuminsProto-Oncogene Proteins c-fosPyramidal CellsCholecystokininFos protein, mouseParvalbuminsProto-Oncogene Proteins c-fosSCG2 protein, humansecretogranin 2, mouseSecretogranin II

Identifiers

PMID33299180
PMCPMC7864877
OpenAlexW3112358871

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.