Observational studyBritish journal of cancer2021
Severity of COVID-19 in children with cancer: Report from the United Kingdom Paediatric Coronavirus Cancer Monitoring Project.
Observational study in British journal of cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Meta-analysis of mortality factors after COVID-19 infection in pediatric oncology patients.Frontiers in oncology · 2025Pooled it
- The impact of immunocompromise on outcomes of COVID-19 in children and young people-a systematic review and meta-analysis.Frontiers in immunology · 2023Pooled it
- COVID-19 outcomes in paediatric cancer: A large scale pooled meta-analysis of 984 cancer patients.Reviews in medical virology · 2022Pooled it
- Guideline
- The quantity and quality of B-cell immunity against SARS-CoV-2 in children with cancer and hematological diseases.Frontiers in immunology · 2025Article
- Clinical Outcomes of Pediatric Cancer Patients with COVID-19: A Cross-Sectional Study.International journal of hematology-oncology and stem cell research · 2024Article
- Challenges in Treating Pediatric Cancer Patients during the COVID-19 Pandemic: Balancing Risks and Care.Viruses · 2024Review
- COVID-19 in Pediatric Patients With Acute Lymphoblastic Leukemia or Lymphoma.JAMA network open · 2024Article
- Caring for a child with cancer during COVID-19 pandemic: an assessment of the parents' perception and stress level.Frontiers in public health · 2024Article
- Profile and Outcomes of Pediatric Hematology and Oncology Patients Diagnosed with COVID-19 in the Philippine General Hospital.Acta medica Philippina · 2024Article
- Increasing SARS-CoV-2 seroprevalence among UK pediatric patients on dialysis and kidney transplantation between January 2020 and August 2021.Pediatric nephrology (Berlin, Germany) · 2023Article
- The Characteristics and Follow-Up of SARS-CoV-2 Infection in Pediatric Oncology Patients.Cureus · 2023Article
- Humoral profiling of pediatric patients with cancer reveals robust immunity following anti-SARS-CoV-2 vaccination superior to natural infection.Pediatric blood & cancer · 2023Article
- Clinical Profile and Short-Term Outcome of Children with Acute SARS-CoV-2 Infection During the First and Second Waves of the Pandemic.Indian journal of pediatrics · 2023Article
- The Impact of the Early COVID-19 Global Pandemic on Children Undergoing Active Cancer Treatment and Their Parents.Current oncology (Toronto, Ont.) · 2023Article
- COVID-19 outcomes in children, adolescents and young adults with cancer.International journal of cancer · 2022Article
- How has the COVID-19 pandemic impacted clinical care and research in Neuro-Oncology?Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia · 2022Review
- Risk factors for severe COVID-19 in hospitalized children in Canada: A national prospective study from March 2020-May 2021.Lancet regional health. Americas · 2022Article
- Twelve-month observational study of children with cancer in 41 countries during the COVID-19 pandemic.BMJ global health · 2022Observational
- Manifestations of COVID-19 infection in children with malignancy: A single-center experience in Jordan.World journal of virology · 2022Article
Corrections and comments
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Authors and funding
14 authors.
Funding
Abstract
backgroundChildren with cancer are frequently immunocompromised. While children are generally thought to be at less risk of severe SARS-CoV-2 infection than adults, comprehensive population-based evidence for the risk in children with cancer is unavailable. We aimed to produce evidence of the incidence and outcomes from SARS-CoV-2 in children with cancer attending all hospitals treating this population across the UK.
methodsRetrospective and prospective observational study of all children in the UK under 16 diagnosed with cancer through data collection from all hospitals providing cancer care to this population. Eligible patients tested positive for SARS-CoV-2 on reverse transcription polymerase chain reaction (RT-PCR). The primary end-point was death, discharge or end of active care for COVID-19 for those remaining in hospital.
resultsBetween 12 March 2020 and 31 July 2020, 54 cases were identified: 15 (28%) were asymptomatic, 34 (63%) had mild infections and 5 (10%) moderate, severe or critical infections. No patients died and only three patients required intensive care support due to COVID-19. Estimated incidence of hospital identified SARS-CoV-2 infection in children with cancer under 16 was 3%.
conclusionsChildren with cancer with SARS-CoV-2 infection do not appear at increased risk of severe infection compared to the general paediatric population. This is reassuring and supports the continued delivery of standard treatment.
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