ArticleScientific reports2020
Development and validation of a timely and representative finite element human spine model for biomechanical simulations.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Advances in Musculoskeletal Modeling of the Thoraco-Lumbar Spine: A Comprehensive Systematic Review.Annals of biomedical engineering · 2025Pooled it
- Three-Dimensional Printing in Pediatric Orthopaedics: Cost Analysis and Emerging Applications.Journal of the Pediatric Orthopaedic Society of North America · 2026Review
- Finite element models of intervertebral disc: recent advances and prospects.Annals of medicine · 2025Review
- Streamlined and efficient patient-specific modeling for lumbar spine segmentation and finite element analysis.Scientific reports · 2025Article
- Development and Assessment of a Novel Generic Finite Element Spine Model for Clinical Applications.International journal for numerical methods in biomedical engineering · 2025Article
- A finite element study of the effect of cross-link stabilisation in a lumbar spine tumour model.Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine · 2025Article
- Effect of individual spinal muscle activities on upright posture using a human body finite element model.Scientific reports · 2025Article
- Development and biomechanical evaluation of a 3D printed analogue of the human lumbar spine.3D printing in medicine · 2025Article
- Biomechanical analysis of spinal cord injury during scoliosis correction surgery.Frontiers in bioengineering and biotechnology · 2024Article
- From MRI to FEM: an automated pipeline for biomechanical simulations of vertebrae and intervertebral discs.Frontiers in bioengineering and biotechnology · 2024Article
- Biomechanical effect of proximal multifidus injury on adjacent segments during posterior lumbar interbody fusion: a finite element study.BMC musculoskeletal disorders · 2023Article
- A smart coating with integrated physical antimicrobial and strain-mapping functionalities for orthopedic implants.Science advances · 2023Article
- Effect of ACDF combined with different degrees of partial resection of uncovertebral joints on cervical stability and degeneration: a three-dimensional finite element analysis.Journal of orthopaedic surgery and research · 2022Article
- Article
- Computational modelling of the scoliotic spine: A literature review.International journal for numerical methods in biomedical engineering · 2021Review
- Feasibility of extracting tissue material properties via cohesive elements: a finite element approach to probe insertion procedures in non-invasive spine surgeries.Medical & biological engineering & computing · 2021Article
- The examination of stress shielding in a finite element lumbar spine inclusive of the thoracolumbar fascia.Medical & biological engineering & computing · 2021Article
- Investigation of Reaction Forces in the Thoracolumbar Fascia during Different Activities: A Mechanistic Numerical Study.Life (Basel, Switzerland) · 2021Article
- Computational Challenges in Tissue Engineering for the Spine.Bioengineering (Basel, Switzerland) · 2021Review
- Biomechanical Effects of a Cross Connector in Sacral Fractures - A Finite Element Analysis.Frontiers in bioengineering and biotechnology · 2021Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Numerous spine Finite Element (FE) models have been developed to assess spinal tolerances, spinal loadings and low back pain-related issues. However, justified simplifications, in terms of tissue decomposition and inclusion, for such a complex system may overlook crucial information. Thus, the purpose of this research was to develop and validate a comprehensive and representative spine FE model inclusive of an accurate representation of all major torso elements. A comprehensive model comprised of 273 tissues was developed via a novel FE meshing method to enhance computational feasibility. A comprehensive set of indirect validation tests were carried out to validate every aspect of the model. Under an increasing angular displacement of 24°-41°, the lumbar spine recorded an increasing moment from 5.5 to 9.3 Nm with an increase in IVD pressures from 0.41 to 0.66 MPa. Under forward flexion, vertical vertebral displacements simulated a 6% and 13% maximum discrepancy for intra-abdominal and intramuscular pressure results, all closely resembling previously documented in silico measured values. The developed state-of-the-art model includes most physiological tissues known to contribute to spinal loadings. Given the simulation's accuracy, confirmed by its validation tests, the developed model may serve as a reliable spinal assessment tool.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.