ArticleScientific reports2020
Longer apneas and hypopneas are associated with greater ultra-short-term HRV in obstructive sleep apnea.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 41 citations in OpenAlex.
- Differential Effects of Sleep Respiratory Event Types on Heart Rate Variability: Central Apnea as the Most Significant.Diagnostics (Basel, Switzerland) · 2026Article
- Hypoxemia and arousals modulate cardiac responses to respiratory events in obstructive sleep apnea.Sleep · 2026Article
- Improving Obstructive Sleep Apnoea Mitigates Dampened Heart Rate Responses to Respiratory Events in Children With Down Syndrome.Journal of sleep research · 2025Article
- Heart Rate Variability (HRV) in Patients with Sleep Apnea and COPD: A Comprehensive Analysis.Journal of clinical medicine · 2025Review
- Effects of Auto-Titrating Mandibular Advancement Device on Autonomic Nervous System in Obstructive Sleep Apnea.Journal of personalized medicine · 2024Article
- The value of circadian heart rate variability for the estimation of obstructive sleep apnea severity in adult males.Sleep & breathing = Schlaf & Atmung · 2024Article
- Independent relationship between sleep apnea-specific hypoxic burden and glucolipid metabolism disorder: a cross-sectional study.Respiratory research · 2024Article
- Heart Rate Variability as a Surrogate Marker of Severe Chronic Coronary Syndrome in Patients with Obstructive Sleep Apnea.Diagnostics (Basel, Switzerland) · 2023Article
- An Obstructive Sleep Apnea - A Novel Public Health Threat.Physiological research · 2023Review
- The Use of Respiratory Effort Improves an ECG-Based Deep Learning Algorithm to Assess Sleep-Disordered Breathing.Diagnostics (Basel, Switzerland) · 2023Article
- The effect of CPAP therapy on heart rate variability in patients with obstructive sleep apnea.Sleep and biological rhythms · 2023Article
- Driver Stress Detection Using Ultra-Short-Term HRV Analysis under Real World Driving Conditions.Entropy (Basel, Switzerland) · 2023Article
- Coupling analysis of heart rate variability and cortical arousal using a deep learning algorithm.PloS one · 2023Article
- Obstructive sleep apnoea-related respiratory events and desaturation severity are associated with the cardiac response.ERJ open research · 2022Article
- Diagnostic Efficacy of Ultra-Short Term HRV Analysis in Obstructive Sleep Apnea.Journal of personalized medicine · 2022Article
- Pulse Oximetry: The Working Principle, Signal Formation, and Applications.Advances in experimental medicine and biology · 2022Article
- Effects of hyperventilation length on muscle sympathetic nerve activity in healthy humans simulating periodic breathing.Frontiers in physiology · 2022Article
- Photoplethysmography in Normal and Pathological Sleep.Sensors (Basel, Switzerland) · 2021Article
- Exploring Ultra-short Heart Rate Variability Metrics in Patients with Diabetes Mellitus: A Reliability Analysis.International journal of applied & basic medical researchArticle
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Corrections and comments
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Low long-term heart rate variability (HRV), often observed in obstructive sleep apnea (OSA) patients, is a known risk factor for cardiovascular diseases. However, it is unclear how the type or duration of individual respiratory events modulate ultra-short-term HRV and beat-to-beat intervals (RR intervals). We aimed to examine the sex-specific changes in RR interval and ultra-short-term HRV during and after apneas and hypopneas of various durations. Electrocardiography signals, recorded as a part of clinical polysomnography, of 758 patients (396 men) with suspected OSA were analysed retrospectively. Average RR intervals and time-domain HRV parameters were determined during the respiratory event and the 15-s period immediately after the event. Parameters were analysed in three pooled sex-specific subgroups based on the respiratory event duration (10-20 s, 20-30 s, and > 30 s) separately for apneas and hypopneas. We observed that RR intervals shortened after the respiratory events and the magnitude of these changes increased in both sexes as the respiratory event duration increased. Furthermore, ultra-short-term HRV generally increased as the respiratory event duration increased. Apneas caused higher ultra-short-term HRV and a stronger decrease in RR interval compared to hypopneas. In conclusion, the respiratory event type and duration modulate ultra-short-term HRV and RR intervals. Considering HRV and the respiratory event characteristics in the diagnosis of OSA could be useful when assessing the cardiac consequences of OSA in a more detailed manner.
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