Evidence map›Paper›PMID 33298877›Full record

ArticleBDJ open2020

Comparison of decayed, missing, filled teeth index between thalassemia major patients and control group in Iran: a systematic review and meta-analysis.

Mahmood Moosazadeh, Nadia Elyassi Gorji, Pegah Nasiri, Ali Malekzadeh Shafaroudi

Open access · goldAbstract read
In one paragraph

Article in BDJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Salivary biomarkers and their association with dental caries and oral health status in children with β-thalassaemia: a case-control study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mahmood MoosazadehGastrointestinal Cancer Research Center, Non-communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran.ORCID http://orcid.org/0000-0002-5452-514X
Nadia Elyassi GorjiStudent Research Committee, Faculty of Dentistry, Mazandaran University of Medical Sciences, Sari, Iran.ORCID http://orcid.org/0000-0003-0062-9354
Pegah NasiriStudent Research Committee, Faculty of Dentistry, Mazandaran University of Medical Sciences, Sari, Iran.ORCID http://orcid.org/0000-0002-0968-2584
Ali Malekzadeh ShafaroudiStudent Research Committee, Faculty of Dentistry, Mazandaran University of Medical Sciences, Sari, Iran. am.shafaroudi@gmail.com.ORCID http://orcid.org/0000-0003-3054-2532
Mazandaran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionScientific evidence of the association between Decayed, Missing, and Filled Teeth (DMFT) and thalassemia are conflicting and difficult to establish conclusions. Therefore, this study aimed to determine the relationship between dental caries (using the DMFT index) and thalassemia major using meta-analysis.

methodsDatabases were searched using such keywords as "Thalassemia," "Caries," "decay," "DMFT," "Iran," and OR operators, AND, and NOT. After the elimination of duplicate documentation, the articles which met the inclusion criteria were selected. Quality assessment was performed based on the Newcastle-Ottawa Quality Checklist. Thereafter, the standardized mean difference of the DMFT index was estimated.

resultsIn eight studies, the mean DMFT was compared between patients with thalassemia major and the control group. In six studies, the mean of this index was higher in patients with thalassemia major than in the control group and in all six of the studies, the differences were statistically significant. The mean standardized difference of DMFT, D, M, and F were reported as 1.36 (0.41, 2.30), 2.63 (0.42, 4.84), 1.65 (-0.14, 3.45), and 0.02 (-1.67, 1.72), respectively.

conclusionThe results of this meta-analysis indicated that DMFT index was more inappropriate in patients with thalassemia, as compared to the control group which represents the higher incidence of dental caries among patients with thalassemia compared to the control group.

Identifiers

PMID33298877
PMCPMC7673014
OpenAlexW3100185655

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.