Evidence map›Paper›PMID 33298613›Full record

ArticleJournal of clinical microbiology2021

Multicenter Evaluation of the Cepheid Xpert Xpress SARS-CoV-2/Flu/RSV Test.

Heba H Mostafa, Karen C Carroll, Rachel Hicken, Gregory J Berry, Ryhana Manji, Elizabeth Smith, Jennifer L Rakeman, Randal C Fowler, Mindy Leelawong, Susan M Butler-Wu and 6 more

Abstract readEvaluation StudyMulticenter Study
In one paragraph

Article in Journal of clinical microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed.

  1. Trial
  2. Article
  3. Evaluation of the high-throughput RespiVMicrobiology spectrum · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Observational
  16. Genomic evolution of influenza during the 2023-2024 season, the johns hopkins health system.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. Performance of the Xpert™ Mpox PCR assay with oropharyngeal, anorectal, and cutaneous lesion swab specimens.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Heba H Mostafa *The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-0274-8966
Karen C Carroll *The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Rachel HickenThe Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Gregory J BerryNorthwell Health Laboratories, Zucker SOM at Hofstra/Northwell, East Garden City, New York, USA.ORCID 0000-0002-0767-6826
Ryhana ManjiNorthwell Health Laboratories, Zucker SOM at Hofstra/Northwell, East Garden City, New York, USA.
Elizabeth SmithNorthwell Health Laboratories, Zucker SOM at Hofstra/Northwell, East Garden City, New York, USA.
Jennifer L RakemanNYC Public Health Laboratory, Department of Health and Mental Hygiene, New York, New York, USA.ORCID 0000-0002-9464-7723
Randal C FowlerNYC Public Health Laboratory, Department of Health and Mental Hygiene, New York, New York, USA.
Mindy LeelawongNYC Public Health Laboratory, Department of Health and Mental Hygiene, New York, New York, USA.ORCID 0000-0002-3702-2938
Susan M Butler-WuKeck School of Medicine of USC, Department of Pathology, Los Angeles, California, USA.ORCID 0000-0001-5372-8706
David QuinteroKeck School of Medicine of USC, Department of Pathology, Los Angeles, California, USA.
Minette Umali-WilcoxKeck School of Medicine of USC, Department of Pathology, Los Angeles, California, USA.
Robert W KwiatkowskiCepheid, Sunnyvale, California, USA.
David H PersingCepheid, Sunnyvale, California, USA.
Fred WeirCepheid, Sunnyvale, California, USA.
Michael J LoeffelholzCepheid, Sunnyvale, California, USA Michael.loeffelholz@cepheid.com.ORCID 0000-0003-3934-089X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the approach of respiratory virus season in the Northern Hemisphere, clinical microbiology and public health laboratories will need rapid diagnostic assays to distinguish severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from influenza virus and respiratory syncytial virus (RSV) infections for diagnosis and surveillance. In this study, the clinical performance of the Xpert Xpress SARS-CoV-2/Flu/RSV test (Cepheid, Sunnyvale, CA, USA) for nasopharyngeal swab specimens was evaluated in four centers: Johns Hopkins Medical Microbiology Laboratory, Northwell Health Laboratories, NYC Public Health Laboratory, and Los Angeles County/University of Southern California (LAC+USC) Medical Center. A total of 319 nasopharyngeal swab specimens, positive for SARS-CoV-2 (

Indexed as

COVID-19HumansInfluenza, HumanMolecular Diagnostic TechniquesNasopharynxSARS-CoV-2Sensitivity and Specificity4-plexCepheidfluinfluenzaRSVSARS-CoV-2

Identifiers

PMID33298613
PMCPMC8106732

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.